DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trs33 and TRAPPC6A

DIOPT Version :9

Sequence 1:	NP_650450.1	Gene:	Trs33 / 41866	FlyBaseID:	FBgn0266722	Length:	152	Species:	Drosophila melanogaster
Sequence 2:	NP_077013.1	Gene:	TRAPPC6A / 79090	HGNCID:	23069	Length:	173	Species:	Homo sapiens

Alignment Length:	173	Identity:	71/173 - (41%)
Similarity:	106/173 - (61%)	Gaps:	21/173 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEEILFDCLHAEIVN--YCLD-------------------SNKEHDLATLEYIGFTTGYRLIER 44
            |::.:||:.||.|:|.  :..|                   ..::..|:.||.:||..|..|.||
Human     1 MADTVLFEFLHTEMVAELWAHDPDPGPGVSAGLRGEEAGATKGQKMSLSVLEGMGFRVGQALGER 65

  Fly    45 LTREVSRFKDELETMKFICTDFWMLIYKKQVDNLRTNNHGMYVVQDKAFRFLTRISPGTKQLEHA 109
            |.||...|::||:.:||:|.|.|:.:::||:|:||||:.|.||:||.:|..|..::.|.:.||.|
Human    66 LPRETLAFREELDVLKFLCKDLWVAVFQKQMDSLRTNHQGTYVLQDNSFPLLLPMASGLQYLEEA 130

  Fly   110 PKFVAFTCGLVRGALSNLGINSTVTAEVQSIPACKFHIEVNRN 152
            |||:||||||:||||..|||.|.|||.|.::|.|||.:.:.::
Human   131 PKFLAFTCGLLRGALYTLGIESVVTASVAALPVCKFQVVIPKS 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trs33	NP_650450.1	TRAPPC6A_Trs33	4..150	CDD:271347	70/166 (42%)
TRAPPC6A	NP_077013.1	TRAPPC6A_Trs33	3..171	CDD:271347	70/167 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3316
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	174	1.000	Inparanoid score	I4071
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1566836at2759
OrthoFinder	1	1.000	-	-		FOG0002452
OrthoInspector	1	1.000	-	-		otm41260
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12817
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2318
SonicParanoid	1	1.000	-	-		X1632
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.890