DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31301 and cdkn2aip

DIOPT Version :9

Sequence 1:	NP_650449.1	Gene:	CG31301 / 41865	FlyBaseID:	FBgn0051301	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001006085.1	Gene:	cdkn2aip / 450065	ZFINID:	ZDB-GENE-041010-188	Length:	312	Species:	Danio rerio

Alignment Length:	308	Identity:	74/308 - (24%)
Similarity:	126/308 - (40%)	Gaps:	86/308 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LDWDVDSYKTEYESDEHWDLRRSFMLAHKDRFEE----------DRLVCLAQTFVNMEFMGCKYP 84
            :.| |:|.:...|:::.|..||.|:|.:.:.|..          |||:.|:..:.|..|:||:||
Zfish    21 VSW-VESLRGHCETNKQWYARREFVLRNMEAFPTIQPGSPSSSLDRLLSLSMVWANHVFLGCRYP 84

  Fly    85 SATMLLVAELSKEIA---ADFRQKREQ---RLKRTFVSASDAAEQRAKGRRAPPLPSTSSPEDSS 143
            ...|..:.|:::.|.   |..|:.|::   :|||..|||:||..|   |::..|    :.|:|.:
Zfish    85 QRVMDKINEMAEGITVIEAPERKTRDEIMGKLKRPAVSAADADYQ---GKKNKP----NEPDDRA 142

  Fly   144 HIK---------RQCF-GGGDPVDLYQDLRFGRLI------VYLAGG-----------RACLQN- 180
            |.|         .:|. ..|.|.: :|.. |.||.      :..|||           |:|:::
Zfish   143 HSKCVVHPATSSHKCGPSPGAPAE-HQPF-FNRLYKAVAWKLVSAGGFGPNLEHFEILRSCVESC 205

  Fly   181 ----SCNIANVKYEERVSRDQPLSD-----------NTKYAELLVNDEVIATGQGESLKAAKKAA 230
                :|...            ||.|           ..:..||......:.||.|....||:..|
Zfish   206 KASLTCVFV------------PLKDIPDLPAGRTQREGQVCELRCCTVYMGTGYGRDESAARAMA 258

  Fly   231 YKQAHLTIQSYCYSIKLNATRDTIKVEKNKDGVNIKVTNESADSPCDP 278
            .|:|....|....::|::..|     .:.:|..::.:.:|.:.|...|
Zfish   259 SKEALKVFQGQKVTVKISRRR-----FRGRDVDDLVLLDEQSRSQAFP 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31301	NP_650449.1	XTBD	34..118	CDD:288780	30/99 (30%)
		G_patch	280..323	CDD:197727
		R3H_NRF	331..390	CDD:100069
cdkn2aip	NP_001006085.1	XTBD	24..115	CDD:288780	25/90 (28%)
cdkn2aip	NP_001006085.1	XTBD	186..276	CDD:288780	20/101 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592761
Domainoid	1	1.000	60	1.000	Domainoid score	I10554
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840