DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31301 and Nkrf

DIOPT Version :9

Sequence 1:	NP_650449.1	Gene:	CG31301 / 41865	FlyBaseID:	FBgn0051301	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_003752181.3	Gene:	Nkrf / 100910054	RGDID:	6500424	Length:	786	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	92/367 - (25%)
Similarity:	153/367 - (41%)	Gaps:	81/367 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 YKTEYESDEHWDLRRSFMLAHKDRFEEDRLVCLAQTFVNMEFMGCKYPSATMLLVAELSKEIAAD 101
            ||.|...:..|.. |.|:..|          |||:.:      |.|          :.||..|||
  Rat   462 YKYEMMPNRTWRC-RVFLQDH----------CLAEGY------GTK----------KTSKHAAAD 499

  Fly   102 FRQKREQRLKRTFVSASDAAEQRAKGRRAPPLPSTSSPEDSSHIKRQCFGGGDPVDLYQDLRFGR 166
            ...|..|:.:.|:.|...:                           ||..|..|....:......
  Rat   500 EALKVLQKTQPTYSSVKSS---------------------------QCHSGSSPKGSGKKKDIKD 537

  Fly   167 LIVYLAGGRACLQNS----CNIANVKYEERVSRDQPLSDNTKY---AELLVNDEVIATGQGESLK 224
            |:||        :||    |.:.:.....|::.:......|..   .::::..||||...|.. |
  Rat   538 LVVY--------ENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVK-K 593

  Fly   225 AAKKAAYKQAHLTIQSYCYSIKLNATRDTIK--VEKNKDGVNIKVTNESADSPCDPKLDPSNKGY 287
            :.|..|..:|..|::....::..|..:.|::  :.:|      ::...||:.....::...|.|.
  Rat   594 SVKYEAAGEAVKTLKKTQPTVINNLKKGTVEDVISRN------EIQGRSAEEAYKQQIKEDNIGN 652

  Fly   288 RMMRLMGWTGGGLGRLKQGREEPVCYLLKNNRNGLGLINPKGN---FADYRRLIENYVRSDDIRD 349
            :::|.|||||||||:..:|..||:....::.|.||||...:.|   ..|..::|.||.||:...|
  Rat   653 QLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHSD 717

  Fly   350 MQFEPTFSKEERTTLHQIARQFGLRSASYGSGESRRLLITKK 391
            :.|....:.:||..:||||:::||:|.|:|.|..|.|::.:|
  Rat   718 LTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRK 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31301	NP_650449.1	XTBD	34..118	CDD:288780	21/80 (26%)
		G_patch	280..323	CDD:197727	17/42 (40%)
		R3H_NRF	331..390	CDD:100069	22/58 (38%)
Nkrf	XP_003752181.3	XTBD	40..>107	CDD:403236
		DSRM_SF	444..505	CDD:412133	18/69 (26%)
		DSRM_SF	545..607	CDD:412133	12/62 (19%)
		G-patch	645..688	CDD:413400	17/42 (40%)
		R3H_NRF	699..758	CDD:100069	22/58 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351032
Domainoid	1	1.000	41	1.000	Domainoid score	I12172
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108121
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.830