Protein Alignment SerRS-m and DIA4

DIOPT Version :9

• Sequence 1: NP_001262599.1
• Gene: SerRS-m / 41862
• FlyBaseID: FBgn0021750
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_011875.1
• Gene: DIA4 / 856402
• SGDID: S000001053
• Length: 446
• Species: Saccharomyces cerevisiae
• Alignment Length: 407
• Identity: 147/407 - (36%)
• Similarity: 218/407 - (53%)
• Gaps: 32/407 - (7%)

  Fly    14 LLLRRQRSHDAKAVEAPIHRPVPTSAQLDELERNVVVRHHKNNVPLIRSLIQEL--DAGDQH-KL 75
            |.|..:|..:.|.::..|     ...|:........::..|..:....:.::.|  ...||: |.
Yeast    52 LQLLGERYQNIKEIDKVI-----ADIQIQRKSIEAQIKKDKTKITEYSAALKALKEQYNDQNSKS 111

  Fly    76 RQLQAEL----EQLPNATHPRLRDYGEEPRELAQYVHRQLTP-----QSRLKEFSELARALNLYR 131
            .:|:.::    :.|||...|.:      |.:..| :.:.:.|     .|..:...::....|:..
Yeast   112 SELKKKILETCKSLPNTLDPTV------PLDAPQ-IEQWINPLKTHKTSEAQAHVDIMLKKNMLD 169

  Fly   132 MDHLGNYTGHKSYYLTGQLATLEQAIIQYALQAVTEHGFKLISVPDILPKEVIESCGM--RTEGE 194
            :....|.||...|||....|.||||::.|||:...|:||.....|.|..||:|::||.  |....
Yeast   170 LQTASNVTGMSWYYLLNDGARLEQALVAYALKKANENGFSSCVPPSITKKELIDACGFNPRDMNN 234

  Fly   195 RTQVYKL-DTGECLSGTSEMALAGFFANKL--LSEDQLPLKVTAVSRCYRAETSGL-QEEKGIYR 255
            ..|:|.| ||...|..|:|:.|||..|||:  |:..:...|:..||||||||.... ::.||:||
Yeast   235 ERQIYALQDTNLGLVATAEIPLAGLGANKVLELNSGECSKKLVGVSRCYRAEAGARGKDTKGLYR 299

  Fly   256 VHQFNKVEMFAICTEEQSEAELEEFKNIEVDLFRRLGLNFRLLDMPPCELGAPAYQKYDIEAWMP 320
            ||:|.|||:|.....|.|...|||.|..::.:...||:..::|:||..:||.||::|||||||||
Yeast   300 VHEFTKVELFCWSKPETSAKVLEEIKQFQISVVEELGIPAKVLNMPSNDLGNPAFKKYDIEAWMP 364

  Fly   321 GRQMWGEISSCSNCTDYQARRLGIRYRRSADGQILHAHTINGTATAIPRLLIALLES-YQKEDG- 383
            ||..:|||||.|||||:|:|||..:||....|::.:.||:||||.||||:::||:|: |....|
Yeast   365 GRGKFGEISSASNCTDFQSRRLNTKYRDDNTGKLEYVHTLNGTAMAIPRVIVALVENFYDPSTGK 429

  Fly   384 IEIPAVLRPFMDNQELI 400
            |.:|..||.||:.|..|
Yeast   430 ISVPECLREFMNGQRYI 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerRS-m	NP_001262599.1	SerS	60..404	CDD:223250	140/361 (39%)
		class_II_aaRS-like_core	100..394	CDD:294192	127/306 (42%)
DIA4	NP_011875.1	serS	1..440	CDD:273066	143/399 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344388
Domainoid	1	1.000	172	1.000	Domainoid score	I760
eggNOG	1	0.900	-	-		E1_COG0172
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6073
Inparanoid	1	1.050	229	1.000	Inparanoid score	I735
Isobase	1	0.950	-	0	Normalized mean entropy	S479
OMA	1	1.010	-	-		QHG54742
OrthoFinder	1	1.000	-	-		FOG0005193
OrthoInspector	1	1.000	-	-		oto99003
orthoMCL	1	0.900	-	-		OOG6_100275
Panther	1	1.100	-	-	LDO	PTHR11778
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1456
SonicParanoid	1	1.000	-	-		X3706
TreeFam	1	0.960	-	-
	16	15.740