DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL9 and MRPL9

DIOPT Version :9

Sequence 1:	NP_524363.3	Gene:	mRpL9 / 41859	FlyBaseID:	FBgn0038319	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_113608.1	Gene:	MRPL9 / 65005	HGNCID:	14277	Length:	267	Species:	Homo sapiens

Alignment Length:	234	Identity:	67/234 - (28%)
Similarity:	114/234 - (48%)	Gaps:	19/234 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SLQQQVRTTFVLKRKYDPPLHKTNEKPRRMRAKNFIYELVDDTLVKKRPNIEVVLKTFVEGVGDK 82
            ||.|. |.|.:::|.:..||.....|| |:..::.:|:||:||..:.:.|:|::|...||.||.:
Human    46 SLSQN-RGTVIVERWWKVPLAGEGRKP-RLHRRHRVYKLVEDTKHRPKENLELILTQSVENVGVR 108

  Fly    83 GDVVSMKPHFVYNKLLLPGLAAYNTPENVAKYAKTE---AEKSTVKHSSPYAQRTVNMLETIVLA 144
            ||:||:|.....|:||..|||.|.:|||...:.:.:   .|....|..:...:.||..|::..|.
Human   109 GDLVSVKKSLGRNRLLPQGLAVYASPENKKLFEEEKLLRQEGKLEKIQTKAGEATVKFLKSCRLE 173

  Fly   145 VVMNKDEPWVLEPWHI-KASLRKTGFYCREECITLPKERIE--GPDLKKENKDFYCTVTINKLEQ 206
            |.|..:..|.|.|..: :...:..|.......:.||:|.|.  |        :::|.||:|.|:.
Human   174 VGMKNNVKWELNPEIVARHFFKNLGVVVAPHTLKLPEEPITRWG--------EYWCEVTVNGLDT 230

  Fly   207 ARLKCRLHHWSTDPSERLPYVLEHWKLQSEPLLDVCSPE 245
            .|:...:.::....::|..|.|..   |:...:...||:
Human   231 VRVPMSVVNFEKPKTKRYKYWLAQ---QAAKAMAPTSPQ 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL9	NP_524363.3	Ribosomal_L9_N	69..114	CDD:279605	21/44 (48%)
MRPL9	NP_113608.1	rplI	95..225	CDD:234659	40/137 (29%)
MRPL9	NP_113608.1	Ribosomal_L9_N	95..140	CDD:396030	21/44 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144598
Domainoid	1	1.000	42	1.000	Domainoid score	I12491
eggNOG	1	0.900	-	-		E1_COG0359
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12696
Inparanoid	1	1.050	85	1.000	Inparanoid score	I5168
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46719
OrthoDB	1	1.010	-	-		D1036760at2759
OrthoFinder	1	1.000	-	-		FOG0005447
OrthoInspector	1	1.000	-	-		oto90975
orthoMCL	1	0.900	-	-		OOG6_110160
Panther	1	1.100	-	-	LDO	PTHR21368
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4174
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800