Protein Alignment Cp190 and ZBTB47

DIOPT Version :10

• Sequence 1: NP_524359.2
• Gene: Cp190 / 41848
• FlyBaseID: FBgn0000283
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: XP_054204415.1
• Gene: ZBTB47 / 92999
• HGNCID: 26955
• Length: 851
• Species: Homo sapiens
• Alignment Length: 682
• Identity: 121/682 - (17%)
• Similarity: 212/682 - (31%)
• Gaps: 223/682 - (32%)

  Fly    21 QNFFNKTDYCDLTLQF-RDNSQLKVHRLVLSACTDYFNVLEQTCEIVDDALIMPNEFQADVVVP- 83
            |..| :.|.||:.|.. ...|....|:.||:|.:.:|:.|     ...:..:...|...:.:.|
Human   111 QRLF-QPDLCDVDLVLVPQRSVFPAHKGVLAAYSQFFHSL-----FTQNKQLQRVELSLEALAPG 169

  Fly    84 ----IVNFMYTGTLEFELKMYGKLLRTAKEMNMTVLL----KLLEAHRRTMENVNRQQRPPSPKG 140
                |:||:||..|........::|..|..:.|..:.    :||:|         |...||.|..
Human   170 GLQQILNFIYTSKLLVNAANVHEVLSAASLLQMADIAASCQELLDA---------RSLGPPGPGT 225

  Fly   141 IRRRTVGQPSS--------------------GLPQQRVL-GPSPQSRNVATPIAQRANTQRGSTG 184
            :   .:.||::                    |||:.... ||.|.|        .|.....|:.|
Human   226 V---ALAQPAASCTPAAPPYYCDIKQEADTPGLPKIYAREGPDPYS--------VRVEDGAGTAG 279

  Fly   185 NTMSRTSGGSNRSPYGDSSNVKQEPTSPFEQLRKGYNNNKRPAQTSLLSPPSKKPSLEEVKEFAE 249
            .|:..|.|                |..||      :...|.........||:....||..:|..|
Human   280 GTVPATIG----------------PAQPF------FKEEKEGGVEEAGGPPASLCKLEGGEELEE 322

  Fly   250 Q--------QRMRKQIAAEYGDND--------PE----------------YDGGMLYDDVHAGDD 282
            :        :|.:.||..|...|:        ||                .||...:.|....||
Human   323 ELGGSGTYSRREQSQIIVEVNLNNQTLHVSTGPEGKPGAGPSPATVVLGREDGLQRHSDEEEEDD 387

  Fly   283 DDDDMPPQPS-------TSKQQSPQGTQTQLEHGSTTIILKQDSPSQTPTIIVKDSSNAKLNHTK 340
            ::::...:..       ..:::...|:|.:.|..      ::|
Human   388 EEEEEEEEEEEGGGSGREEEEEEEGGSQGEEEEE------EED---------------------- 424

  Fly   341 IIAEVLRQYPHIVKGHKNIKLKIMPNTPAAPTEKSAPATVKPPANQSSATTSPHKKLHVSFKADK 405
                          ||...:.:........|:|:...::.:....:..|......:...|.:||
Human   425 --------------GHSEQEEEEEEEEEEGPSEQDQESSEEEEGEEGEAGGKQGPRGSRSSRAD- 474

  Fly   406 STPLITAQQKAASSQQKSGT--SQTTGNQG-------------TGANPPANTAAAQKRRIDSKTM 455
            ..|......::..:.::.||  .:..|.:|             :...|||......|.:::.|..
Human   475 PPPHSHMATRSRENARRRGTPEPEEAGRRGGKRPKPPPGVASASARGPPATDGLGAKVKLEEKQH 539

  Fly   456 HALIAQGAENTTGPWLCLRCGVNGRPISIPSYRGFRRHLINTHKETIDPALCEHCGWRSVNNREL 520
            |.              |.:|     |....:.....:|:..||...   .:|:.||.|.:...||
Human   540 HP--------------CQKC-----PRVFNNRWYLEKHMNVTHSRM---QICDQCGKRFLLESEL 582

  Fly   521 HFH--------------------MYMEHQTKSLLYTFAE----CALCNQSYRTKGELEAHINEVH 561
            ..|                    ::..|:...:::.:||    |.:|.:.:.|...:..|: ..|
Human   583 LLHRQTDCERNIQCVTCGKAFKKLWSLHEHNKIVHGYAEKKFSCEICEKKFYTMAHVRKHM-VAH 646

  Fly   562 TDDNKQQCIYCNKVFEQELQLYRHMKSYHKEQ 593
            |.|....|..|.|.|::.:.|..|...:..|:
Human   647 TKDMPFTCETCGKSFKRSMSLKVHSLQHSGEK 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB_POZ_CP190-like	16..125	CDD:349620	27/113 (24%)
		COG5236	<471..>594	CDD:227561	30/147 (20%)
		C2H2 Zn finger	540..568	CDD:275371	7/27 (26%)
		C2H2 Zn finger	569..586	CDD:275371	5/16 (31%)
		PTZ00121	<709..1075	CDD:173412
ZBTB47	XP_054204415.1	BTB_POZ_ZBTB47_ZNF651	105..219	CDD:349540	28/122 (23%)
		PLN03086	<526..600	CDD:178635	16/95 (17%)
		C2H2 Zn finger	542..563	CDD:275368	4/25 (16%)
		C2H2 Zn finger	569..588	CDD:275368	7/18 (39%)
		C2H2 Zn finger	596..616	CDD:275368	1/19 (5%)
		COG5048	624..>705	CDD:227381	14/56 (25%)
		C2H2 Zn finger	626..646	CDD:275368	4/20 (20%)
		C2H2 Zn finger	654..674	CDD:275368	6/19 (32%)
		SFP1	<676..759	CDD:227516	1/3 (33%)
		C2H2 Zn finger	682..702	CDD:275368
		C2H2 Zn finger	710..730	CDD:275368
		COG5048	734..>805	CDD:227381
		C2H2 Zn finger	738..758	CDD:275368
		C2H2 Zn finger	766..782	CDD:275368