Protein Alignment Cp190 and Cp190

DIOPT Version :10

• Sequence 1: NP_524359.2
• Gene: Cp190 / 41848
• FlyBaseID: FBgn0000283
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: XP_321271.6
• Gene: Cp190 / 1281321
• VectorBaseID: AGAMI1_011978
• Length: 1229
• Species: Anopheles gambiae
• Alignment Length: 1350
• Identity: 472/1350 - (34%)
• Similarity: 628/1350 - (46%)
• Gaps: 401/1350 - (29%)

  Fly     3 EVKSVKVDNWGVFFLQKLQNFFNKTDYCDLTLQFRDNSQLKVHRLVLSACTDYFNVLEQTCEIVD 67
            |.||||||||||||||||||||||||:|||||||.||||||||||||||||||||.||..||:.|
Mosquito     9 EAKSVKVDNWGVFFLQKLQNFFNKTDHCDLTLQFNDNSQLKVHRLVLSACTDYFNHLENVCEMYD 73

  Fly    68 DALIMPNEFQADVVVPIVNFMYTGTLEFELKMYGKLLRTAKEMNMTVLLKLLEAHRRTMENVNRQ 132
            |.||||.:.||||:||||||||||||||:..||.:||:||.:||||||||||||||:|...:.:|
Mosquito    74 DVLIMPMDLQADVIVPIVNFMYTGTLEFQYNMYDRLLKTATDMNMTVLLKLLEAHRQTSSRIVKQ 138

  Fly   133 ------QRPPSPKG--IRRRTVGQPSSGLPQQR-------VLGPSPQSRNVATPIAQRANTQRGS 182
                  |.|...:|  :.:...||...|||.||       .:|..|:     .|:|::.....|
Mosquito   139 PVLLNKQAPRPQRGGPVYQGNHGQQRGGLPVQRGPPSGLPAVGSRPR-----LPLARQPVHSYG- 197

  Fly   183 TGNTMSRTSGGSNRSPYGDS-----------------------------SNVKQEPTSPFEQLRK 218
             |.:|:..:.|...:..|.|                             ...|:|.|||||:|||
Mosquito   198 -GKSMAHAAAGPKDAKPGPSRFDDGEMGDGFEGSFDGITYETKPLLTADQVKKEEETSPFEKLRK 261

  Fly   219 GYNNN---KRPAQTSLLSPPSKKPSLEEVKEFAEQQRMRKQIAAEYGDNDPEYDGGMLYDDVHAG 280
            ||.|.   |||:..||.|||:|||:|||||||.|..|||.|:..: .|:.|:|    :.||.|..
Mosquito   262 GYTNANVVKRPSSGSLTSPPAKKPNLEEVKEFTEAARMRSQLTTD-DDDSPDY----VDDDTHFN 321

  Fly   281 DDDDDDMPPQPST----SKQQSPQGTQTQLEHGSTTIILKQD--SPSQTPTII----VKDSSNAK 335
            ||||:|..|..|.    :|..|.||..|     :..|::||:  ||.|...::    |||.| ..
Mosquito   322 DDDDEDYQPPASVKAALAKSASQQGATT-----TKQIVIKQESKSPGQGSNVLKQITVKDDS-GN 380

  Fly   336 LNHTKIIAEVLRQYPHIVKGHKNIKLKIMPNTPAAPTEKSAPATVKPPANQSSA-------TTSP 393
            ::|.|||:|||::|||:||.:||||||||..    |:..:...|....::.|||       |.:|
Mosquito   381 VDHAKIISEVLKKYPHLVKKNKNIKLKIMQK----PSPNAGNNTTSGASSSSSAAPKMDIRTATP 441

  Fly   394 HK-------KLHVSFKAD--KSTPLITAQQKAASSQQKSGTSQTTGNQGTGANPPANTAAAQKRR 449
            .|       :...:.::|  |..|..|:|..::|      |:.|||....|..         .:.
Mosquito   442 LKQDQSMVRRATANIRSDMAKGGPSTTSQSSSSS------TAATTGKPSGGGT---------TKT 491

  Fly   450 IDSKTMHALIAQGAENTTGPWLCLRCGVNGRPISIPSYRGFRRHLINTHKETIDPALCEHCGWRS 514
            ||:||||||||:|||||||||||||||:||||||||||:.|..|||:.|||.||..:|||||:::
Mosquito   492 IDAKTMHALIAKGAENTTGPWLCLRCGINGRPISIPSYKAFYNHLIHKHKERIDVRICEHCGFKA 556

  Fly   515 -VNNRELHFHMYMEHQTKSLLYTFAECALCNQSYRTKGELEAHINEVHTDD---NKQQCIYCNKV 575
             ..|..|.:|.:..|..|..| .|..|..|:....|..:|..|..|||...   :.|||||||||
Mosquito   557 QQRNPHLLYHWHTVHNIKPAL-RFPRCGECDHVAMTADDLAKHEEEVHASSGGGDLQQCIYCNKV 620

  Fly   576 FEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGSQDEEE----------EAEGDEEQEPEQTGK 630
            |.:|::||.|||..||::|:.||:::.||:|  ..|.|||          .|.||        ||
Mosquito   621 FAKEMELYDHMKEQHKQRAIADGVLEFTDDE--DYQTEEELTSPQTKTYGSAAGD--------GK 675

  Fly   631 VRILSDISLP-----------------ATSAITVQQAQ--------------------------- 651
            ::|||:|:||                 :...||::.:.
Mosquito   676 IKILSNITLPPAKGTYGGAEGKSGAGGSARPITLEPSSEAEALSNVASGIATSLTLVGDNGVVLD 740

  Fly   652 ----QEQLQEEDVEQVQQE-----------VKFVGADGNEVELTDEQRKEILSQLNQQQAGATAG 701
                |.|..|.::..|..|           .|.|.|||.|:.||..|:.||:|||  |..|.:..
Mosquito   741 DPNYQNQYIEAELASVHGEHASGGAAGDGMPKLVTADGTELLLTQSQKDEIISQL--QSTGGSGN 803

  Fly   702 GVVMVLSEPE-----------------------------AEH------------VKQETDEKSLA 725
            .|||||:|..                             :||            |....||.|.|
Mosquito   804 DVVMVLNEDNFSVGSTIQLGEGVQIVDTVMYSQQAADAGSEHNDSQKSDAKAADVTASEDENSQA 868

  Fly   726 GTE--------------EEYDDSQIYSELGAADSVESAKKNIADESKESIDNLEWAENLIAESEE 776
            ...              ||.||||......|:|..:    .:.|:.....|:::.:..:.:|:.|
Mosquito   869 SVSLSEDKPVVDKEVSLEEGDDSQASRRTDASDKPD----EVDDDGNTMDDDVDMSGEVTSETNE 929

  Fly   777 ---QSNKE----------PKSDKPR------DDI--------SEKLK---ELTGDWTEDEND--- 808
               |:.|:          |.:|...      ||:        |:|||   ||.|||:||..:
Mosquito   930 TLQQAVKDQLMEMDDDELPDADTSADAAVKDDDLDDSEDRQQSDKLKLISELEGDWSEDTAEEQQ 994

  Fly   809 ------DDVDDKPATAELASE--------LANKD-----PEPTVHEEEDDIDLALQSLHKGPEEA 854
                  |:..:|||..|.|:|        ||.|.     |||.
Mosquito   995 PPPPVADEPVEKPAKREKATEKKPVAAAPLAGKSSAAAKPEPA---------------------- 1037

  Fly   855 TEEKASEESVTS--ADDAVDAVPNINSQPEKMDVDSEAADEKASKAEVQIKKEAELENDQEEFIK 917
              :|||.|||.|  .:...||.|:..   :|..|::    ||.|..|:
Mosquito  1038 --KKASSESVKSKEKESLADAAPDTQ---QKKAVET----EKLSGKEI----------------- 1076

  Fly   918 EDSPIPHSDSVAELREAVTASEGEDDVHLEADNIRKELLDELIAEAEKPDQEKDIVQSEENATTE 982
                    |.:.            ||.:.||.      ||||..||...::|.:.|.:..::..|
Mosquito  1077 --------DKLL------------DDWNNEAK------LDELSNEAGDLEKEIEKVTTGGSSVAE 1115

  Fly   983 ALDRSVTDEDDLVPPT---------QVSTEQMEIDEPAAEKAAENNED-TRTADEKEAVEDKPNQ 1037
            |:....|||::  |.|         :...||.|..:.|::.||:..|. |::.||:|.|..|..:
Mosquito  1116 AVAVDPTDEEE--PDTTAKPIKTESEPEEEQEEEGDDASKDAAKQKEKVTKSDDERETVSPKGKK 1178

  Fly  1038 TQDVTTAEKPT-----LESAKAGDEATSGEAASVDK-VKSLISEWGDDDE 1081
            ....|.|.:..     .|...||||....::||..| |.||:.||.:||:
Mosquito  1179 NGTATAASEKVEATSEPEDDDAGDEDDKDKSASKSKEVSSLLGEWDEDDD 1228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB_POZ_CP190-like	16..125	CDD:349620	88/108 (81%)
		COG5236	<471..>594	CDD:227561	63/126 (50%)
		C2H2 Zn finger	540..568	CDD:275371	8/30 (27%)
		C2H2 Zn finger	569..586	CDD:275371	11/16 (69%)
		PTZ00121	<709..1075	CDD:173412	112/490 (23%)
Cp190	XP_321271.6	None