Protein Alignment Hsc70-4 and ECM10

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_010884.1
• Gene: ECM10 / 856682
• SGDID: S000000756
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 599
• Identity: 301/599 - (50%)
• Similarity: 413/599 - (68%)
• Gaps: 28/599 - (4%)

  Fly     2 SKAP--AVGIDLGTTYSCVGVFQHGKV-EIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 62
            :|.|  .:|||||||.|.|.:.: ||| .||.|.:|:|||||.|||| |.|||:|:.||.|..:|
Yeast    23 TKIPDAVIGIDLGTTNSAVAIME-GKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVIN 86

  Fly    63 PTQTIFDAKRLIGRKFDDAAVQSDMKHWPFEVVS-ADGKPKIEVTYKDEKKTFFPEEISSMVLTK 126
            ...|:|..||||||:|:||.||.|:...||::|. ::|...:|.    ..:|:.|.:|...:|.|
Yeast    87 SENTLFATKRLIGRRFEDAEVQRDINQVPFKIVKHSNGDAWVEA----RNRTYSPAQIGGFILNK 147

  Fly   127 MKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVG 191
            |||||||||.|:|.|||:||||||||:|||||||||.|.||||||::|||||||:||||||..
Yeast   148 MKETAEAYLAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDKSE-- 210

  Fly   192 ERNVLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTN 256
            .:.:.:|||||||||:|||.||:||||||||.|||||||||||..|:...:..||::...||:.:
Yeast   211 PKVIAVFDLGGGTFDISILDIDNGIFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSND 275

  Fly   257 KRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTD------FYTSITRARFEELNADLFRSTMD 315
            :.|::|:|.|.|:||..|||:  .|.||:..|...|      .....:|.:.|.:.|.|...|:|
Yeast   276 RMAVQRIREAAEKAKIELSST--LSTEINLPFITADAAGPKHIRMPFSRVQLENITAPLIDRTVD 338

  Fly   316 PVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAIL 380
            ||:|||:||::..|.|.|::||||.:|:|||...::.|| ||:.:|::|||||||.|||:|||:|
Yeast   339 PVKKALKDARITASDISDVLLVGGMSRMPKVADTVKKLF-GKDASKAVNPDEAVALGAAIQAAVL 402

  Fly   381 HGDKSQEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEG 445
            .|    ||.|:||||||||||||||.|||.:.||.||:|||.|::|.|:|.:..|..|.::|::|
Yeast   403 SG----EVTDVLLLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQG 463

  Fly   446 ERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRL 510
            ||.:.|||.|:|.|.|:||||||:|.||||||||||||||:||:|.:.:::|::.||:....| |
Yeast   464 ERELVKDNKLIGNFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLASHKDSSITVAGASG-L 527

  Fly   511 SKEDIERMVNEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCN 575
            |..:|:|||||||:|:|:|..::..|...|..:....:.:.::.|  .:.|:..:|...:.|:.:
Yeast   528 SDTEIDRMVNEAERYKNQDRARRNAIETANKADQLANDTENSIKE--FEGKLDKTDSQRLKDQIS 590

  Fly   576 ETIKWLDANQLADK 589
            ...:.:..:|..|:
Yeast   591 SLRELVSRSQAGDE 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	301/599 (50%)
ECM10	NP_010884.1	dnaK	29..644	CDD:234715	299/593 (50%)