Protein Alignment: Hsc70-4 and LHS1

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_012850.1
• Gene: LHS1
• SGDID: S000001556
• Length: 881
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 168/696 (24%)
• Similarity: 306/696 (44%)
• Gaps: 105/696 (15%)

  Fly     2 SKAPAVGIDLG-TTYSCVGVFQHGKVEIIANDQGNRTTPSYVAF-----------TDTERLIGDA 54
            |.|..:|:|.| .....:.|.....:|::...:..|...|.::.           ...||:.|.|
Yeast    18 SLAAVLGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSA 82

  Fly    55 AKNQVAMNPTQTIFDAKRLIGRKFDDAAVQS--DMKHWPFEVVSADGKPKIEVTYKDEKKTFFPE 117
            ..:.....|..|:...|.|:|:..:|....:  ..:|...|:||.:   :..:.:..:...:..|
Yeast    83 VGSLATRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTN---RSTIAFLVDNVEYPLE 144

  Fly   118 EISSMVLTKMKETAEAYL----GKT---VTNAVITVPAYFNDSQRQATKDAGTI-AGLNVLRIIN 174
            |:.:|.:.::...|.:.|    .:|   |.....|:|.:|:..||:|..||.:| .|:....:::
Yeast   145 ELVAMNVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVS 209

  Fly   175 EPTAAAIAYGLDKKAV--GE-RNVLIFDLGGGTFDVSILSI---DDG----IFEVKSTAGDTHLG 229
            |..:.|:.:.|.::..  || ::.:::|:|.|:...|:.||   :|.    ..|.:....:.|||
Yeast   210 EGMSVAVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLG 274

  Fly   230 GEDFDNRLVTHFVQEFKRKH----KKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEG 290
            |..|...:.:....:|...|    ..:|..|.:||.::..|.|:||..||::::|||.|:||...
Yeast   275 GAKFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIESLIND 339

  Fly   291 TDFYTSITRARFEELNADLFRSTMDPVEKALR------DAKLDKSVIHDIVLVGGSTRIPKVQRL 349
            .||.|||||..|||..||.....:.|:..|:.      ...|.:  |:.::|.|||:|||.||..
Yeast   340 IDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPE--INGVILAGGSSRIPIVQDQ 402

  Fly   350 LQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDK---SQEVQDLLLLD--VTPLSLGIETAGGV 409
            |..|.:.:::.:::|.||     :||...::.|.|   |.:.:.|.::|  |...|..:.....:
Yeast   403 LIKLVSEEKVLRNVNADE-----SAVNGVVMRGIKLSNSFKTKPLNVVDRSVNTYSFKLSNESEL 462

  Fly   410 MSVLIKRNTTIPTKQTQTFTTYSDNQP----------GVLIQVYEGERAMTKDNNLLGKFELSGI 464
            ..| ..|.:..|.| |...|..:|:.|          |.|.:.........|::....|.. ||:
Yeast   463 YDV-FTRGSAYPNK-TSILTNTTDSIPNNFTIDLFENGKLFETITVNSGAIKNSYSSDKCS-SGV 524

  Fly   465 PPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKI----TITNDKGRL--SKEDIE-RMVNEA 522
                    ...:|||:.::.:.::..:......||.|    .|.|...||  :.||:| :.::.:
Yeast   525 --------AYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQIKNKGSRLAFTSEDVEIKRLSPS 581

  Fly   523 EKYRNE------DEKQKETIAAK---NGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETI 578
            |:.|..      |::.||....:   |.|||..::.:..|.:|    ::..:...:.:::.:|.:
Yeast   582 ERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDD----EVMQNGPKSQVEELSEMV 642

  Fly   579 K----WL-DANQLADKEEYEHRQKELEGVCNPIITKLYQGAGFPP 618
            |    || ||:...|.|:...|.:|: |:....| :||..:...|
Yeast   643 KVYLDWLEDASFDTDPEDIVSRIREI-GILKKKI-ELYMDSAKEP 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	167/688 (24%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	106/417 (25%)
LHS1	NP_012850.1	DnaK	17..809	CDD:223520	168/696 (24%)
		HYOU1-like_NBD	23..430	CDD:212672	106/417 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR19375
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000