DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Hsc70-4 and SSE2

Sequence 1:NP_001262586.1 Gene:Hsc70-4 FlyBaseID:FBgn0266599 Length:651 Species:Drosophila melanogaster
Sequence 2:NP_009728.1 Gene:SSE2 SGDID:S000000373 Length:693 Species:Saccharomyces cerevisiae

Alignment Length:649 Identity:180/650 (28%)
Similarity:317/650 (49%) Gaps:66/650 (10%)


  Fly     8 GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKR 72
            |:|||...|.:.|.::..::::.|:..||:|||.|.|....|.:|::.|.:...|...|:.:.||
Yeast     6 GLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKR 70

  Fly    73 LIGRKFDDAAVQSDMKHWPFEVVS-ADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYLG 136
            :||.||.|.....:.|.:..::|. .:||..:||.:..:...|...::::|.:.|:|.|.:....
Yeast    71 IIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETK 135

  Fly   137 KTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAV-----GERNVL 196
            .::|:..:.||.::::.||....||..|||||.:||:|:.||||::||:.|..:     ..|.:.
Yeast   136 SSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIG 200

  Fly   197 IFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALR 261
            :.|:|..|:..||::...|..:|..||.|.|.||.|||..:..||..:||.|:|.|:..|.:|..
Yeast   201 LVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYN 265

  Fly   262 RLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKL 326
            |:..|.|:.|:.||::|.|...::|:.:..|..:.::|...|||...|.:....|:..||..|||
Yeast   266 RILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKL 330

  Fly   327 DKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDL 391
            ..:.|..:.::||:||||.:::.:.|:| ||.|:.::|.|||||.|||...|| | ..:..|:..
Yeast   331 TVNDIDFVEIIGGTTRIPVLKKSISDVF-GKPLSSTLNQDEAVAKGAAFICAI-H-SPTLRVRPF 392

  Fly   392 LLLDVTPLSLG------------IETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYE 444
            ...|:.|.|:.            :|        :...|::.|:.:..|.....|..   :..||.
Yeast   393 KFEDIDPYSVSYTWDKQVDDEDRLE--------VFPANSSYPSTKLITLHRTGDFS---MKAVYT 446

  Fly   445 GERAMTK-DNNLLGKFELSGIP-PAPRGVPQIEVTFDIDANGI---------LNVTALE------ 492
            ....:.| .:..:.|:..:|:. |..:....::|....|.:|:         .::|..|      
Yeast   447 HPSKLPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPE 511

  Fly   493 -------------RSTNKENKITITNDKGRLSKEDIERMVNEAEKYRNEDEKQKETIAAKNGLES 544
                         ..|.|::.:.:|.....|:..::..::.:..:.||:|:...||...||.||.
Yeast   512 DAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEE 576

  Fly   545 YCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWL--DANQLADKEEYEHRQKELEGVCNPI 606
            |.:.::|.|| |......||:::..:.:....|..||  |.:. :.|.:|..:.:||..:.|.|
Yeast   577 YIYTLRAKLD-DEYSDFASDAEKEKLKNMLATTENWLYGDGDD-STKAKYIAKYEELASLGNII 638

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Hsc70-4NP_001262586.1 PTZ00009 1..612 CDD:240227 180/650 (28%)
HSPA1-2_6-8-like_NBD 6..381 CDD:212675 129/379 (34%)
SSE2NP_009728.1 HSP70 4..644 CDD:331774 180/650 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG0443
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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