Protein Alignment Hsc70-4 and SSA3

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_009478.1
• Gene: SSA3 / 852203
• SGDID: S000000171
• Length: 649
• Species: Saccharomyces cerevisiae
• Alignment Length: 653
• Identity: 483/653 - (73%)
• Similarity: 553/653 - (84%)
• Gaps: 6/653 - (0%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            ||:  |||||||||||||..|.:.:|||||||||||||||||||||||||||||||||.|:||..
Yeast     1 MSR--AVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHN 63

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||||||..|.:|.||:||:|:|.||||.::|.||.|.|||.|||||||||:|||||
Yeast    64 TVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKET 128

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||.|||.||.:||:||||||||||||||||||||||:|||||||||||||||||||||...|.||
Yeast   129 AENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNV 193

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||:||||:|:||||:|||||||||||||||||.|...|||||.|||::.|:|:|
Yeast   194 LIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSL 258

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            ||||||.|||||.||||:|.||||||||||.|||||:||||||||.|||||||::||||.|:|:|
Yeast   259 RRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSK 323

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            ||||.|.:||||||||||||:|:|:.|.|||||.|:|||||||||||||||||||.||:|.:.||
Yeast   324 LDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQD 388

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||:|:.||.||:|||||:::||:||:||||||||||:||||..||||||
Yeast   389 LLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNL 453

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            |||||||||||||||||||:|||||||||||||:|||:.|.|.||||||||||||||:||:|||:
Yeast   454 LGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVS 518

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            ||||||.:||::.|.:.|||.||||.|.:|.|::|.:.|.|:.:.|...:.....|||.||||:|
Yeast   519 EAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQ 583

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLY-QGAGFPPGGMPGGPGGMPGAAGAAGAAGAG-GAGPTIE 648
            .|..:||:.|||||||:.|||:||.| .|||..||.  |..||.||:...:||.|.| ..|||:|
Yeast   584 AASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGA--GESGGFPGSMPNSGATGGGEDTGPTVE 646

  Fly   649 EVD 651
            |||
Yeast   647 EVD 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	462/611 (76%)
SSA3	NP_009478.1	PTZ00009	4..649	CDD:240227	479/646 (74%)