Protein Alignment: Hsc70-4 and SSA2

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_013076.1
• Gene: SSA2
• SGDID: S000003947
• Length: 639
• Species: Saccharomyces cerevisiae
• Alignment Length: 652
• Identity: 482/653 (74%)
• Similarity: 551/653 (84%)
• Gaps: 14/653 (2%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |||  |||||||||||||..|.:.:|:|||||||||||||:|.|||||||||||||||.||||..
Yeast     1 MSK--AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPAN 63

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||.|:|..||.||||:||:::..||||:|:|.:|.|.|.|.||:||||||.|||||
Yeast    64 TVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKET 128

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||:|||..|.:||:||||||||||||||||||||||||||||||||||||||||||||. .|.:|
Yeast   129 AESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKG-KEEHV 192

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||:|||:|||||||:|||||||||||||||||.||:||||||:||||:||:|||
Yeast   193 LIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRAL 257

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||.|.|:||||||||.||||||||||||||.|||||||:|||||.|||||
Yeast   258 RRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAK 322

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            ||||.:.:||||||||||||||:|:.|.|||||.|:|||||||||||||||||||.||:|.:.||
Yeast   323 LDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQD 387

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||||:.||.||:|||||:::.|:||:||||||||||:|||||.||||||
Yeast   388 LLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNL 452

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||||||||||||||||||||||:|:||||||:|:|:.|.|.||||||||||||||||||:||.
Yeast   453 LGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVA 517

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            ||||::.||||:.:.||:||.|||..:::|.|:.|..  .|:..:|:..:..|..|||.|||:|.
Yeast   518 EAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNT 580

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGAGPTIEE 649
            .|.|||::.:.|||:.|.|||::||||..|.|.|..||| |||.|.|..|        .|||:||
Yeast   581 TATKEEFDDQLKELQEVANPIMSKLYQAGGAPEGAAPGGFPGGAPPAPEA--------EGPTVEE 637

  Fly   650 VD 651
            ||
Yeast   638 VD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	462/611 (76%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	305/375 (81%)
SSA2	NP_013076.1	PTZ00009	4..639	CDD:240227	478/646 (74%)
		HSPA1-2_6-8-like_NBD	4..378	CDD:212675	305/375 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0443
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	944	1.000	Inparanoid score	I36
Isobase	1	0.950		0	Normalized mean entropy	S49
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000062
OrthoInspector	1	1.000				T133810
orthoMCL	1	0.900				OOG5_126588
Panther	1	1.100			LDO	PTHR19375
Phylome	1	0.910		0.909	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R573
TreeFam	1	0.960
	12	11.810