DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Hsc70-4 and SSA2

Sequence 1:NP_001262586.1 Gene:Hsc70-4 FlyBaseID:FBgn0266599 Length:651 Species:Drosophila melanogaster
Sequence 2:NP_013076.1 Gene:SSA2 SGDID:S000003947 Length:639 Species:Saccharomyces cerevisiae

Alignment Length:652 Identity:482/653 (74%)
Similarity:551/653 (84%) Gaps:14/653 (2%)


  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |||  |||||||||||||..|.:.:|:|||||||||||||:|.|||||||||||||||.||||..
Yeast     1 MSK--AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPAN 63

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||.|:|..||.||||:||:::..||||:|:|.:|.|.|.|.||:||||||.|||||
Yeast    64 TVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKET 128

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||:|||..|.:||:||||||||||||||||||||||||||||||||||||||||||||. .|.:|
Yeast   129 AESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKG-KEEHV 192

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||:|||:|||||||:|||||||||||||||||.||:||||||:||||:||:|||
Yeast   193 LIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRAL 257

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||.|.|:||||||||.||||||||||||||.|||||||:|||||.|||||
Yeast   258 RRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAK 322

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            ||||.:.:||||||||||||||:|:.|.|||||.|:|||||||||||||||||||.||:|.:.||
Yeast   323 LDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQD 387

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||||:.||.||:|||||:::.|:||:||||||||||:|||||.||||||
Yeast   388 LLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNL 452

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||||||||||||||||||||||:|:||||||:|:|:.|.|.||||||||||||||||||:||.
Yeast   453 LGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVA 517

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            ||||::.||||:.:.||:||.|||..:::|.|:.|..  .|:..:|:..:..|..|||.|||:|.
Yeast   518 EAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNT 580

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGAGPTIEE 649
            .|.|||::.:.|||:.|.|||::||||..|.|.|..||| |||.|.|..|        .|||:||
Yeast   581 TATKEEFDDQLKELQEVANPIMSKLYQAGGAPEGAAPGGFPGGAPPAPEA--------EGPTVEE 637

  Fly   650 VD 651
            ||
Yeast   638 VD 639

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Hsc70-4NP_001262586.1 PTZ00009 1..612 CDD:240227 462/611 (76%)
HSPA1-2_6-8-like_NBD 6..381 CDD:212675 305/375 (81%)
SSA2NP_013076.1 PTZ00009 4..639 CDD:240227 478/646 (74%)
HSPA1-2_6-8-like_NBD 4..378 CDD:212675 305/375 (81%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG0443
Hieranoid 1 1.000
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 944 1.000 Inparanoid score I36
Isobase 1 0.950 0 Normalized mean entropy S49
OMA 1 1.010
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 FOG0000062
OrthoInspector 1 1.000 T133810
orthoMCL 1 0.900 OOG5_126588
Panther 1 1.100 LDO PTHR19375
Phylome 1 0.910 0.909 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R573
TreeFam 1 0.960
1211.810

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