Protein Alignment Hsc70-4 and hspa1b

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001093532.1
• Gene: hspa1b / 798846
• ZFINID: ZDB-GENE-060503-867
• Length: 639
• Species: Danio rerio
• Alignment Length: 653
• Identity: 525/653 - (80%)
• Similarity: 576/653 - (88%)
• Gaps: 16/653 - (2%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |:|..::||||||||||||||||||||||||||||||||||||||||||||||||||||||||..
Zfish     1 MAKGLSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNN 65

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |||||||||||||||..||||||.|||:|:|.|||||::|.||.|.|||:|||||||||.||:|.
Zfish    66 TIFDAKRLIGRKFDDQVVQSDMKLWPFKVISEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREI 130

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||||||..|.||||||||||||||||||||||.||||||||||||||||||||||||...|||||
Zfish   131 AEAYLGHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGRKGERNV 195

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||||:|:|||||||:|||||||||||||||:|.|||:|||||||||::.||||:
Zfish   196 LIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRAV 260

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||:||||||||||||.||||||||||||||||:|||.|:|||||||||||
Zfish   261 RRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELNAELFRGTLDPVEKALRDAK 325

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            :|||.|.|||||||||||||:|:||||.|||::||||||||||||||||||||||.||.|:.|||
Zfish   326 MDKSQIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSENVQD 390

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||.|||||||||||||:.||||||||||||||.|:|||||||||||||:||||||||||||
Zfish   391 LLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAMTKDNNL 455

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||:|:||||||||||||||||||||||||||:|.::||.|||||||||||||||||||||||.
Zfish   456 LGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKEDIERMVQ 520

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            :||||:.|||.|:|.|||||.||||.|:||.|::::||:.|||:.|:..|:|||.|.:.||:.||
Zfish   521 DAEKYKAEDEVQREKIAAKNALESYAFSMKNTVEDENLRGKISEQDKKKIIDKCTEVVSWLENNQ 585

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAG--AAGAGGAGPTIE 648
            ||:||||||.|||||.||||||::|||| |.||             ||..|  |......|||||
Zfish   586 LAEKEEYEHHQKELESVCNPIISRLYQG-GAPP-------------AGGCGFQAQPESSQGPTIE 636

  Fly   649 EVD 651
            |||
Zfish   637 EVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	507/610 (83%)
hspa1b	NP_001093532.1	PTZ00009	1..639	CDD:240227	523/651 (80%)