Protein Alignment Hsc70-4 and LOC680121

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_038944691.1
• Gene: LOC680121 / 680121
• RGDID: 1595502
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 654
• Identity: 553/654 - (84%)
• Similarity: 598/654 - (91%)
• Gaps: 11/654 - (1%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            |||.|||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||.
  Rat     1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNCTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||:||||.||||||||||.||:..|:||::|.||.|.|:|:|||:||||||||||.
  Rat    66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEI 130

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            |||||||||||||:|||||||||||||||||||||||||||||||||||||||.||||...||||
  Rat   131 AEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYVLDKKVGAERNV 195

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            |||||||||||||||:|:|||||||||||||||||||||||:|.||:.|||||||||::.||||:
  Rat   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAV 260

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325
            |||||||||||||||||||||||||||:||.||||||||||||||||||||.|:|||||||||||
  Rat   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAK 325

  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390
            ||||.|||||||||||||||:|:||||.|||||||||||||||||||||||||||.||||:.|||
  Rat   326 LDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQD 390

  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 LLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455

  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
            ||||||:||||||||||||||||||||||||||:|:::||.|||||||||||||||||||||||.
  Rat   456 LGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQ 520

  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585
            |||||:.|||||::.:::||.||||.||||||::::.|:.||:|.|:..|||||||.|.|||.||
  Rat   521 EAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQ 585

  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGA--GPTI 647
            .|:|||:||:|||||.|||||||||||.||..||||||| |||        ||..:|||  ||||
  Rat   586 TAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGG--------GAPPSGGASSGPTI 642

  Fly   648 EEVD 651
            ||||
  Rat   643 EEVD 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	526/610 (86%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	332/374 (89%)
LOC680121	XP_038944691.1	PTZ00009	1..613	CDD:240227	527/611 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1055	1.000	Domainoid score	I23
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136446
Inparanoid	1	1.050	1101	1.000	Inparanoid score	I218
OMA	1	1.010	-	-		QHG53894
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm45832
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	O	PTHR19375
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.970