Protein Alignment Hsc70-4 and HSPA13

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 430
• Identity: 168/430 - (39%)
• Similarity: 251/430 - (58%)
• Gaps: 50/430 - (11%)

  Fly     7 VGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFD 69
            :||||||||..||||  ..|||::|.::.|:.:.||.|:|||.:..:|..:......||..||:|
Human    34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYD 98

  Fly    70 AKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAY 134
            |||.||:.|....:::::..:||:|::.:|..:..|| .:|..|..||.:.|.:|.|:||.||||
Human    99 AKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLLLKLKEMAEAY 162

  Fly   135 LGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFD 199
            ||..|.||||:|||.|:..||.:|.:|..:|||.:||:||||||||:||||.|..|  .:||:.|
Human   163 LGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADV--FHVLVID 225

  Fly   200 LGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLR 264
            |||||.|||:|:...|:|..::.:|:..|||:||:.||:.:..::..:.: ..:.:.|..:.|||
Human   226 LGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTY-GFVPSRKEEIHRLR 289

  Fly   265 TACERAK--RTLSSSTQASIEI-------------------DSLFEGTD---------------- 292
            .|.|..|  .||..|.|.|:.:                   |.|....|
Human   290 QAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKS 354

  Fly   293 ------FYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQ 351
                  |.|.|:|..|:.||.|||:..:.|:::.|::..|:|:.|.::||||||||||::::::|
Human   355 GESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQ 419

  Fly   352 DLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDL 391
            :.| ||:.|.|::||.||..|.|:||.|..|....:|..|
Human   420 EFF-GKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSAL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	168/430 (39%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	165/418 (39%)
HSPA13	NP_008879.3	HSPA13-like_NBD	12..463	CDD:212679	168/430 (39%)
		PRK13930	32..442	CDD:237564	161/412 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		3/36 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820