Protein Alignment Hsc70-4 and hsp70l

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001107061.1
• Gene: hsp70l / 560210
• ZFINID: ZDB-GENE-050321-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 649
• Identity: 523/649 - (80%)
• Similarity: 576/649 - (88%)
• Gaps: 10/649 - (1%)

  Fly     3 KAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTI 67
            |..|:||||||||||||||||||||||||||||||||||||||||||||||||||||||||..|:
Zfish     5 KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTV 69

  Fly    68 FDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAE 132
            |||||||||:|||..||||||||.|:|||..||||:.|.:|.|.|||.|||||||||.||||.||
Zfish    70 FDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAE 134

  Fly   133 AYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLI 197
            ||||:.|||||||||||||||||:||||||.||||||||||||||||||||||||....||||||
Zfish   135 AYLGQKVTNAVITVPAYFNDSQRRATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLI 199

  Fly   198 FDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRR 262
            |||||||||||||:|:|||||||:|||||||||||||||:|.|||:|||||||||::.|||||||
Zfish   200 FDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRR 264

  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLD 327
            |||||||||||||.|:|||||||||:||.||||||||||||||.:||||.|:|||||||||||:|
Zfish   265 LRTACERAKRTLSPSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMD 329

  Fly   328 KSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLL 392
            |:.|||||||||||||||:|:||||.|||:|||||||||||||||||||||||.||.|..|||||
Zfish   330 KAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLL 394

  Fly   393 LLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLG 457
            ||||.|||||||||||||:.||||||||||||||||||||||||||||||:||||||||||||||
Zfish   395 LLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLG 459

  Fly   458 KFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEA 522
            ||||:||||||||||||||||||||||||||:|.::||.|:|:|||||||||||||:|||||.||
Zfish   460 KFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNRITITNDKGRLSKEEIERMVQEA 524

  Fly   523 EKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLA 587
            :||:.||:.|:|.|:|||.||||.||||.::::||||.|||:.|:..:::||||.:.||:.||||
Zfish   525 DKYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVVEKCNEAVSWLENNQLA 589

  Fly   588 DKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEVD 651
            |||||||:.||||.||||:|:||||      ||||.|..|    |.|..|:||...||||||||
Zfish   590 DKEEYEHQLKELEKVCNPVISKLYQ------GGMPAGGCG----AQARAASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	502/608 (83%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	322/374 (86%)
hsp70l	NP_001107061.1	PTZ00009	5..643	CDD:240227	521/647 (81%)
		HSPA1-2_6-8-like_NBD	8..383	CDD:212675	322/374 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575289
Domainoid	1	1.000	1033	1.000	Domainoid score	I26
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm6456
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R573
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.690