DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsc70-4 and ankrd45

DIOPT Version :9

Sequence 1:	NP_001262586.1	Gene:	Hsc70-4 / 41840	FlyBaseID:	FBgn0266599	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001018606.1	Gene:	ankrd45 / 553808	ZFINID:	ZDB-GENE-050522-311	Length:	224	Species:	Danio rerio

Alignment Length:	99	Identity:	24/99 - (24%)
Similarity:	54/99 - (54%)	Gaps:	6/99 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   516 ERMVNEAEKYRNEDEKQKETIA---AKNGLESYCFNMKATL-DEDNLKTKISDSDRTTILDKCNE 576
            |:.|:.|.:|...|  ..|.:|   ||..|:::...::|.: |::.::.|::..|:...::.|:.
Zfish   115 EKAVDVARRYDKLD--CAEYLAWAEAKQNLQAFIQEVRAIVADQEKVQGKLNKEDKNICINTCSA 177

  Fly   577 TIKWLDANQLADKEEYEHRQKELEGVCNPIITKL 610
            ..:|::..:.|..:.:..::|.||.|..|::.||
Zfish   178 KSEWINNTRTATAQVFIEQKKLLEDVLAPVLLKL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	24/99 (24%)
Hsc70-4	NP_001262586.1	HSPA1-2_6-8-like_NBD	6..381	CDD:212675
ankrd45	NP_001018606.1	ANK	<42..133	CDD:238125	6/19 (32%)
		ANK repeat	46..78	CDD:293786
		Ank_2	51..143	CDD:289560	9/29 (31%)
		ANK repeat	80..111	CDD:293786
		ANK repeat	113..143	CDD:293786	9/29 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900