Protein Alignment Hsc70-4 and Hsp68

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 461/648 - (71%)
• Similarity: 550/648 - (84%)
• Gaps: 15/648 - (2%)

  Fly     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFD 69
            ||:|||||||||||||||:|||||||||||||||||||||||:||||||||||||||||..::||
  Fly     2 PAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFD 66

  Fly    70 AKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAY 134
            |||||||:|||:.:|.|:|||||:|::.:|||||.|.:|...|.|.|||||||||||||||||||
  Fly    67 AKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAY 131

  Fly   135 LGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFD 199
            ||.||.:|||||||||||||||||||||.|||:|||||||||||||:||||||...|||||||||
  Fly   132 LGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196

  Fly   200 LGGGTFDVSILSIDDG-IFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRL 263
            |||||||||||:||:| :|||:||||||||||||||||||.||.:|||||:||||.:|.||||||
  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRL 261

  Fly   264 RTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDK 328
            |||.|||||||||||:||:|||:|:||.|||:.::|||||||..||||:|::||||||:|||:||
  Fly   262 RTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDK 326

  Fly   329 SVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLL 393
            |.|||||||||||||||||.|||:.|.||.||.|||||||||||||:|||||.||||.|::|:||
  Fly   327 SQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLL 391

  Fly   394 LDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 458
            :||.|||||||||||||:.||:||:.||.||::|||||:||||.|.|||:|||||:|||||:||.
  Fly   392 VDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGT 456

  Fly   459 FELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAE 523
            |:|:|:||||||||:|:||||:||||||||||.|:.|.....|||.|||||||:.||:||::|||
  Fly   457 FDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAE 521

  Fly   524 KYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLAD 588
            ||..|||:.::.|||:|.||:|.|.:|..  .:|...:||.:|:::|:::|:|.:||||:|..|:
  Fly   522 KYAEEDERHRQRIAARNQLETYLFGVKEA--AENGGDRISAADKSSIVERCSEAMKWLDSNTTAE 584

  Fly   589 KEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEVD 651
            |||||::.||||..|:||:||:::|         ||.|..   |...|....|..|||:||||
  Fly   585 KEEYEYKLKELEQFCSPIMTKMHKG---------GGDGQQ---APNFGQQAGGYKGPTVEEVD 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	447/607 (74%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	303/375 (81%)
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	459/646 (71%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	303/375 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750