Protein Alignment Hsc70-4 and hspa5

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_998223.1
• Gene: hspa5 / 378848
• ZFINID: ZDB-GENE-031001-11
• Length: 650
• Species: Danio rerio
• Alignment Length: 620
• Identity: 397/620 - (64%)
• Similarity: 501/620 - (80%)
• Gaps: 6/620 - (0%)

  Fly     2 SKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAF-TDTERLIGDAAKNQVAMNPTQ 65
            |....:|||||||||||||:::|:|||||||||||.||||||| |:.|||||||||||:..||..
Zfish    24 SVGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPEN 88

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTY-KDEKKTFFPEEISSMVLTKMKE 129
            |:|||||||||.:.|::||.|:|::||:|:....||.|::.. ..:.|||.|||||:||||||||
Zfish    89 TVFDAKRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMKE 153

  Fly   130 TAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERN 194
            ||||||||.||:||:||||||||:||||||||||||||||:|||||||||||||||||:. ||:|
Zfish   154 TAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRD-GEKN 217

  Fly   195 VLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRA 259
            :|:|||||||||||:|:||:|:|||.:|.|||||||||||.|::.||::.:|:|..||:..:.||
Zfish   218 ILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRA 282

  Fly   260 LRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDA 324
            :::||...|:|||.||:..||.|||:|.|||.||..::|||:|||||.|||||||.||:|.|.|:
Zfish   283 VQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDS 347

  Fly   325 KLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQ 389
            ...|..|.:||||||||||||:|:|:::.|||||.::.|||||||||||||||.:|.|:  :|..
Zfish   348 DPKKPDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGE--EETG 410

  Fly   390 DLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNN 454
            ||:||||.||:|||||.||||:.||.|||.:|||::|.|:|.|||||.|.|:||||||.:||||:
Zfish   411 DLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNH 475

  Fly   455 LLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMV 519
            |||.|:|:||||||||||||||||:||.||||.|||.::.|..:||||||||:.||:.|||||||
Zfish   476 LLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMV 540

  Fly   520 NEAEKYRNEDEKQKETIAAKNGLESYCFNMKATL-DEDNLKTKISDSDRTTILDKCNETIKWLDA 583
            ||||::.:||:|.||.|.::|.||||.:::|..: |::.|..|:|..|:..|.....|.|:||:|
Zfish   541 NEAERFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKEAIEKAVEEKIEWLEA 605

  Fly   584 NQLADKEEYEHRQKELEGVCNPIITKLYQGAGFPP 618
            :|.||.||::.::||||.|..||::|||..||.||
Zfish   606 HQDADLEEFQAKKKELEEVVQPIVSKLYGSAGGPP 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	392/612 (64%)
hspa5	NP_998223.1	PTZ00009	29..641	CDD:240227	396/615 (64%)