Protein Alignment: Hsc70-4 and hspa4a

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_999881.1
• Gene: hspa4a
• ZFINID: ZDB-GENE-040426-2832
• Length: 833
• Species: Danio rerio
• Alignment Length: 690
• Identity: 204/691 (30%)
• Similarity: 345/691 (50%)
• Gaps: 97/691 (14%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAK 71
            ||.|:|.....|.|.:.|.:|.:||:..:|.|||:|:|....|.||.|||:||..|...|:...|
Zfish     4 VGFDVGFQSCYVAVARAGGIETVANEYSDRCTPSFVSFGPRNRSIGAAAKSQVVTNCKNTVQGFK 68

  Fly    72 RLIGRKFDDAAVQSDMKHWPFEVVS-ADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            |..||.|.|..|::......:::.. .:|...|:|.|.:|:|.|..|::::|:|||:|||||:.|
Zfish    69 RFHGRAFSDPYVETTQSSLVYDLAQMPNGTTGIKVMYMEEEKLFGIEQVTAMLLTKLKETAESAL 133

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAV-----GERNV 195
            .|.|.:.||:||:||.|::|::..||..|||||.||::|:.||.|:|||:.|:.:     ..|.|
Zfish   134 KKPVADCVISVPSYFTDAERRSVMDAAQIAGLNCLRLMNDTTAVALAYGIYKQDLPAPEEKPRTV 198

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            :..|:|...:.||..:.:.|..:|..:|.|..|||:|||..||.||.:||.:|:|.|:.:..|||
Zfish   199 VFVDVGHAGYQVSACAFNKGKLKVLGSAFDPELGGKDFDEVLVKHFCEEFAQKYKLDVRSKPRAL 263

  Fly   261 RRLRTACERAKRTLS-SSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDA 324
            .||...||:.|:.:| :|:...:.|:......|..:.:.||:||||.|.|......|::..:...
Zfish   264 VRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVSSKLNRAKFEELCAGLLAKVEAPLQSIMEQT 328

  Fly   325 KLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQ 389
            :|.|..|:.:.::||::|||.::..:...| ||||:.::|.|||||.|.|:|.|||  ..:.:|:
Zfish   329 RLKKEDIYAVEIIGGASRIPAIKERISKFF-GKELSTTLNLDEAVARGCALQCAIL--SPAFKVR 390

  Fly   390 DLLLLDVTPLSLGIETAG----GVMSV-LIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAM 449
            :..:.||.|..:.::...    ||... :..:|...|..:..||..   .:|..|...|...:|:
Zfish   391 EFSITDVVPYPISLKWTSAADEGVSDCEVFPKNHAAPFSKVLTFYR---KEPFTLEAYYNNPKAL 452

  Fly   450 TKDNNLLGKFELSGIPPAPRG-VPQIEVTFDIDANGILNVTA---------------LERST--- 495
            ...:..:|:|.:..:.|...| ..:::|...::.:|:.:|::               :|..|
Zfish   453 PYPDPTIGQFTIHKVVPQASGESSKVKVKVRVNVHGVFSVSSASLVELLKPGEGEEPMETDTPAK 517

  Fly   496 NKENKITITND---------KGRLSK----EDIERMVNEAEKYRN-------------------- 527
            ::|||:.:..:         |.:..|    ||:|....:.::.:|
Zfish   518 DEENKMQVDQEAQKAQADDQKEQADKKSDTEDMETSPEDKQEKKNDQPPQAKKAKVKTKTVDLPI 582

  Fly   528 -------------------------EDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDR 567
                                     :|:.:||...|||.:|.|.:.|:..| ...|:..:|:::|
Zfish   583 MNSLQWQLASDALNLFMENEGKMIMQDKLEKERNDAKNYVEEYVYEMRDKL-HGVLENFVSEAER 646

  Fly   568 TTILDKCNETIKWL-DANQLADKEEYEHRQKELEGVCNPI 606
            .:...|..:|..|| :..:...|:.|..:..||:.:.:||
Zfish   647 DSFSLKLEDTENWLYEEGEDQQKQVYIDKLAELKKLGDPI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	204/691 (30%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	149/381 (39%)
hspa4a	NP_999881.1	NBD_sugar-kinase_HSP70_actin	2..384	CDD:302596	149/383 (39%)
		HSP70	3..692	CDD:278441	204/691 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900