Protein Alignment: Hsc70-4 and Hspa12a

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_017444569.1
• Gene: Hspa12a
• RGDID: 1305531
• Length: 691
• Species: Rattus norvegicus
• Alignment Length: 661
• Identity: 143/662 (22%)
• Similarity: 245/662 (37%)
• Gaps: 213/662 (32%)

  Fly     7 VGIDLGTTYS-----------CVGVFQHGKVEIIANDQG--NRTTPSYVAFTDTERL--IGDAAK 56
            |.||.|||.|           |:.|.:..:    ..|.|  |:.||:.:..|...:.  .|.||:
  Rat    75 VAIDFGTTSSGYAYSFTKEPECIHVMRRWE----GGDPGVSNQKTPTTILLTPERKFHSFGYAAR 135

  Fly    57 N-QVAMNPTQTIFDAKR-LIGRKF-------DDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKK 112
            : ...::|.    :||: |...||       .|..:.:|:       .:|:|| |::..   |..
  Rat   136 DFYHDLDPN----EAKQWLYLEKFKMKLHTTGDLTMDTDL-------TAANGK-KVKAL---EIF 185

  Fly   113 TFFPEEISSMVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGL------NVLR 171
            |:..:......|.::.:.|.:....:....||||||.:....:|..::|...|||      ..|.
  Rat   186 TYALQYFKEQALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAGLASPENSEQLI 250

  Fly   172 IINEPTAAAI---------AYGLDKKAV------------------------------------- 190
            |..||.||:|         ...|..|||
  Rat   251 IALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQSRTFLVENVIG 315

  Fly   191 --------GERNVLIFDLGGGTFDVSI--LSIDDGIFE--VKSTAGDTHLGGEDFD-NRLV---- 238
                    |::.|:: |.||||.|:::  :.:.:|..:  .|:|.|.....|.|:: .:|:
  Rat   316 EIWSELEEGDKYVVV-DSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLLCKIF 379

  Fly   239 -THFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFY-------- 294
             ..|:::||.|       ...|...|..|.|..||..:......:.|...|...|:|
  Rat   380 GEDFIEQFKIK-------RPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSV 437

  Fly   295 ----------------TSITRARFEELNADLFRSTMDPVEKALRD--AKLDKSVIHDIVLVGGST 341
                            ..:.|...:.:|| ||:.|:|.:.:.|||  .|.:.|.:..:.||||..
  Rat   438 EHALRKSNVDFVKWSSQGMLRMSPDAMNA-LFKPTIDSIIEHLRDLFQKPEVSTVKFLFLVGGFA 501

  Fly   342 RIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAV-QAAILHGDKSQEVQDLLLLDV--TPLSLGI 403
            ..|.:|:.:|..|..|  .:.|.|.:.   |..: :.|:|.|      .|..::.|  :||:.|:
  Rat   502 EAPLLQQAVQAAFGDK--CRIIIPQDV---GLTILKGAVLFG------LDPAVIKVRRSPLTYGV 555

  Fly   404 ETAGGVMS-----------VLIKRNTT---------IPTKQT--------QTFTTYSDNQPGVLI 440
                ||::           :|:|..|.         |...|:        :::|....:|..::|
  Rat   556 ----GVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKRSYTPAKPSQLVIII 616

  Fly   441 QVYEGER---------AMTKDNNLLGKFELSGIP----PAPRGVPQIEVTFDIDANGILNVTALE 492
            .:|..|.         .:.|...|  :.:|:|..    ||.|.:..:....|.:    :..||::
  Rat   617 NIYSSENDDVSFITDPGVKKCGTL--RLDLTGTSGAAVPARREIQTLMQFGDTE----IKATAVD 675

  Fly   493 RSTNKENKITI 503
            .:|:|..|:.|
  Rat   676 IATSKSVKVGI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	143/662 (22%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	111/495 (22%)
Hspa12a	XP_017444569.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900