Protein Alignment: Hsc70-4 and hsp70.3

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_571472.2
• Gene: hsp70.3
• ZFINID: ZDB-GENE-110713-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 649
• Identity: 527/650 (81%)
• Similarity: 578/650 (89%)
• Gaps: 10/650 (2%)

  Fly     3 KAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTI 67
            |..|:||||||||||||||||||||||||||||||||||||||||||||||||||||||||..|:
Zfish     5 KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTV 69

  Fly    68 FDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAE 132
            |||||||||:|||..||||||||.|:|||..||||:.|.:|.|.|||.|||||||||.||||.||
Zfish    70 FDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAE 134

  Fly   133 AYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLI 197
            ||||:.||||||||||||||||||||||||.||||||||||||||||||||||||....||||||
Zfish   135 AYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLI 199

  Fly   198 FDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRR 262
            |||||||||||||:|:|||||||:|||||||||||||||:|.|||:|||||||||::.|||||||
Zfish   200 FDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRR 264

  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLD 327
            |||||||||||||||:|||||||||:||.||||||||||||||.:||||.|:|||||||||||:|
Zfish   265 LRTACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMD 329

  Fly   328 KSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLL 392
            |:.|||||||||||||||:|:||||.|||:|||||||||||||||||||||||.||.|..|||||
Zfish   330 KAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLL 394

  Fly   393 LLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLG 457
            ||||.|||||||||||||:.||||||||||||||||||||||||||||||:||||||||||||||
Zfish   395 LLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLG 459

  Fly   458 KFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEA 522
            ||||:||||||||||||||||||||||||||:|.::||.|:|||||||||||||||:|||||.||
Zfish   460 KFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQEA 524

  Fly   523 EKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLA 587
            :||:.||:.|:|.|:|||.||||.||||.::::||||.|||:.|:..:::||||.:.||:.||||
Zfish   525 DKYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQLA 589

  Fly   588 DKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEVD 651
            |||||||:.||||.||||:|:||||      ||||.|..|    |.|.||:||...||||||||
Zfish   590 DKEEYEHQLKELEKVCNPVISKLYQ------GGMPAGGCG----AQARGASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	506/609 (83%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	325/375 (87%)
hsp70.3	NP_571472.2	PTZ00009	5..643	CDD:240227	526/648 (81%)
		HSPA1-2_6-8-like_NBD	8..383	CDD:212675	325/375 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C281053021
eggNOG	1	0.900				E1_COG0443
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D180577at33208
OrthoFinder	1	1.000				FOG0000062
OrthoInspector	1	1.000				T128641
orthoMCL	1	0.900				OOG5_126588
Panther	1	1.100			O	PTHR19375
Phylome	1	0.910		0.714	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R573
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.780