Protein Alignment: Hsc70-4 and Hspa4l

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_006232359.1
• Gene: Hspa4l
• RGDID: 1306528
• Length: 1017
• Species: Rattus norvegicus
• Alignment Length: 796
• Identity: 211/797 (26%)
• Similarity: 343/797 (43%)
• Gaps: 204/797 (26%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAK 71
            ||||||.....:.|.:.|.:|.|||:..:|.||:.::.....|.||:|||:|:..|...||...|
  Rat   183 VGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFK 247

  Fly    72 RLIGRKFDDAAVQSDMKHWPFEVVS-ADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            :|.||.|||..||::....|:|:.. .:|...::|.|.:|::.|..|:::.|:|.|:|||:|..|
  Rat   248 KLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENAL 312

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG--------LDKKAVGE 192
            .|.|.:.||::|::|.|::|::...|..:||||.||::||.||.|:|||        ||:|   .
  Rat   313 KKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEK---P 374

  Fly   193 RNVLIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNK 257
            |||:..|:|...:.||:.:.:.|..:|.:|..|.:|||.:||..||.:|..|||.|:|.::..|.
  Rat   375 RNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKAKYKINVKENS 439

  Fly   258 RALRRLRTACERAKRTLS-SSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKAL 321
            |||.||...||:.|:.:| :::...:.|:......|..:.:.||:||:|.|.|......|::..:
  Rat   440 RALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKAVM 504

  Fly   322 RDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQ 386
            ..|.|.:..|:.|.:|||:||||.|:..:...|. |:::.::|.|||||.|.|:|.|||  ..:.
  Rat   505 DQANLQREDINSIEIVGGATRIPAVKEQVTRFFL-KDISTTLNADEAVARGCALQCAIL--SPAF 566

  Fly   387 EVQDLLLLDVTPLSL------GIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEG 445
            :|::..:.|:.|.|:      ..|...|...|..| |...|..:..||   ...:|..|...|..
  Rat   567 KVREFSITDLVPYSVTLSWKTSFEEGTGECEVFSK-NHPAPFSKVITF---HKKEPFELEAFYTN 627

  Fly   446 ERAMTKDNNLLGKFELSGIPPAPRG-VPQIEVTFDIDANGILNVTA------------------- 490
            ...:...:..:|.|.:..:.|...| ..:::|...|:.:||.:|.:
  Rat   628 LHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAPME 692

  Fly   491 LERSTNK--------------------------ENKITITNDKGRLSKEDIERMVNEAEK----- 524
            .|.|.|:                          |.:|..|..|.:....|.:..:|:..|
  Rat   693 TEASKNEGKEDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKAKAPPSDKQDRINQTIKKGKIK 757

  Fly   525 ----------YRN------------------EDEKQKETIAAKNGLESYCFNMKATL-------- 553
                      ||.                  :|:.:||...|||.:|.|.::.:..|
  Rat   758 SIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFI 822

  Fly   554 ---DEDNLKTKISDSD-----------RTTILDKCNE---------------------------- 576
               |.:.|...:.|::           :...:||..|
  Rat   823 TPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDKLQELKKYGQPIQMKYVEHEERPKALNDLGKK 887

  Fly   577 ---TIKWLDANQLADKEEYEH-------------------------------------------- 594
               .:|.::|::..| |.|:|
  Rat   888 IQLVLKVIEAHRNKD-ERYDHLDPAEMEKVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIV 951

  Fly   595 -RQKELEGVCNPIITK 609
             :.|||:..||||:.|
  Rat   952 TKSKELDNFCNPIVYK 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	211/797 (26%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	146/384 (38%)
Hspa4l	XP_006232359.1	HSPA4L_NBD	181..563	CDD:212688	146/386 (38%)
		HSP70	182..873	CDD:278441	197/700 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900