Protein Alignment Hsc70-4 and hsp-6

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001370558.1
• Gene: hsp-6 / 178873
• WormBaseID: WBGene00002010
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 325/632 - (51%)
• Similarity: 424/632 - (67%)
• Gaps: 51/632 - (8%)

  Fly     3 KAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTQT 66
            |...:|||||||.|||.:.:....::|.|.:|.|||||.|||| |.|||:|..||.|...|...|
 Worm    30 KGHVIGIDLGTTNSCVSIMEGKTPKVIENAEGVRTTPSTVAFTADGERLVGAPAKRQAVTNSANT 94

  Fly    67 IFDAKRLIGRKFDDAAVQSDMKHWPFEVVSA-DGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            :|..||||||:::|..||.|:|..|:::|.| :|...:|.    :.|.:.|.::.:.||.|||||
 Worm    95 LFATKRLIGRRYEDPEVQKDLKVVPYKIVKASNGDAWVEA----QGKVYSPSQVGAFVLMKMKET 155

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            ||:|||.||.|||:||||||||||||||||||.|:||||||:||||||||:||||||.| |::.:
 Worm   156 AESYLGTTVNNAVVTVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKDA-GDKII 219

  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260
            .::||||||||||||.|..|:||||||.|||.|||||||:.||.|.|.|||::...|||.:.:|:
 Worm   220 AVYDLGGGTFDVSILEIQKGVFEVKSTNGDTFLGGEDFDHALVHHLVGEFKKEQGVDLTKDPQAM 284

  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTD----FYTSITRARFEELNADLFRSTMDPVEKAL 321
            :|||.|.|:||..|||:||..|.:..:.....    ....:|||:||::..||.:.|::|..|||
 Worm   285 QRLREAAEKAKCELSSTTQTDINLPYITMDQSGPKHLNLKLTRAKFEQIVGDLIKRTIEPCRKAL 349

  Fly   322 RDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQ 386
            .||::..|.|.|::||||.:|:||||..:|::| ||..:|::|||||||.|||:|.|:|.||
 Worm   350 HDAEVKSSQIADVLLVGGMSRMPKVQATVQEIF-GKVPSKAVNPDEAVAMGAAIQGAVLAGD--- 410

  Fly   387 EVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTK 451
             |.|:||||||||||||||.||:|:.||.||||||||::|.|:|.:|.|..|.|:|::|||.|..
 Worm   411 -VTDVLLLDVTPLSLGIETLGGIMTKLITRNTTIPTKKSQVFSTAADGQTQVQIKVFQGEREMAT 474

  Fly   452 DNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIE 516
            .|.|||:|.|.|||||||||||:|||||||||||:||:|.:|.|.||.:|.| ...|.|||:.||
 Worm   475 SNKLLGQFSLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDRGTGKEQQIVI-QSSGGLSKDQIE 538

  Fly   517 RMVNEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDE----------DNLKTKISDSDRTTIL 571
            .|:.||||...||.|:||.:...|..|....:.:|.:.|          :.|:|||:|:.:  ||
 Worm   539 NMIKEAEKNAAEDAKRKELVEVINQAEGIIHDTEAKMTEFADQLPKDECEALRTKIADTKK--IL 601

  Fly   572 D-KCNETIKWLDANQLADKEEYEHRQKELEGVCNPI---ITKLYQGA 614
            | |.|||                  .:.::..||.:   ..||::.|
 Worm   602 DNKDNET------------------PEAIKEACNTLQQQSLKLFEAA 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	324/628 (52%)
hsp-6	NP_001370558.1	dnaK	30..646	CDD:234715	325/632 (51%)