Protein Alignment Hsc70-4 and hsp70.2

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001349289.1
• Gene: hsp70.2 / 100535101
• ZFINID: ZDB-GENE-110405-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 649
• Identity: 525/649 - (80%)
• Similarity: 577/649 - (88%)
• Gaps: 10/649 - (1%)

  Fly     3 KAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTI 67
            |..|:||||||||||||||||||||||||||||||||||||||||||||||||||||||||..|:
Zfish     5 KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTV 69

  Fly    68 FDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAE 132
            |||||||||:|||..||||||||.|:|||..||||:.|.:|.|.|||.|||||||||.||||.||
Zfish    70 FDAKRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAE 134

  Fly   133 AYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLI 197
            ||||:.||||||||||||||||||||||||.||||||||||||||||||||||||....||||||
Zfish   135 AYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLI 199

  Fly   198 FDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRR 262
            |||||||||||||:|:|||||||:|||||||||||||||:|.|||:|||||||||::.|||||||
Zfish   200 FDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRR 264

  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLD 327
            |||||||||||||||:|||||||||:||.||||||||||||||.:||||.|:|||||||||||:|
Zfish   265 LRTACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMD 329

  Fly   328 KSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLL 392
            |:.|||||||||||||||:|:||||.|||:|||||||||||||||||||||||.||.|..|||||
Zfish   330 KAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLL 394

  Fly   393 LLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLG 457
            ||||.|||||||||||||:.||||||||||||||||:|||||||||||||:||||||||||||||
Zfish   395 LLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFSTYSDNQPGVLIQVFEGERAMTKDNNLLG 459

  Fly   458 KFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEA 522
            ||||:||||||||||||||||||||||||||:|.::||.|:|||||||||||||||:|||||.||
Zfish   460 KFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQEA 524

  Fly   523 EKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLA 587
            :.|:.||:.|:|.|:|||.||||.||||.::::||||.|||:.|:..:::||||.:.||:.||||
Zfish   525 DNYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQLA 589

  Fly   588 DKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEVD 651
            |||||||:.||||.||||:|:||||      ||||.|..|    |.|.||:||...||||||||
Zfish   590 DKEEYEHQLKELEKVCNPVISKLYQ------GGMPAGGCG----AQARGASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	503/608 (83%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	324/374 (87%)
hsp70.2	NP_001349289.1	HSP70	5..643	CDD:331774	523/647 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1033	1.000	Domainoid score	I26
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm6456
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820