Protein Alignment SIDL and trs130

DIOPT Version :9

• Sequence 1: NP_650431.1
• Gene: SIDL / 41833
• FlyBaseID: FBgn0038303
• Length: 1145
• Species: Drosophila melanogaster
• Sequence 2: NP_588342.1
• Gene: trs130 / 2538961
• PomBaseID: SPCC285.14
• Length: 1150
• Species: Schizosaccharomyces pombe
• Alignment Length: 1327
• Identity: 256/1327 - (19%)
• Similarity: 452/1327 - (34%)
• Gaps: 406/1327 - (30%)

  Fly     4 KPIITYSGSCPLFRSLESQILNAIPLDTCEWRRTFQRPTKHVRLEAQAQQFNVAALEKYKQGDWS 68
            |||:.|.....|:.|:.:.|.:.|||...:|..::|. .||. :.:...:| :..||::...|.|
pombe     5 KPIVQYYDPFDLWPSIATDIESKIPLRNLQWVESYQY-KKHT-ITSLDLEF-LPWLEEFSSQDTS 66

  Fly    69 ----ILEHPILHIFVTECNDVDTYKATIREAIDIWLKTLTSYGVSDWMILLVETLDMRKTKNFMP 129
                :|..|::::......|.:.||...:.....|.:.::......|||:||......|..|.:.
pombe    67 KDPTLLNIPLVNMLFLPEQDGEIYKTQHKPLATKWFQKVSKNENQSWMIVLVAEAQQAKRSNSLR 131

  Fly   130 RT-----------TVLDKIRLDFGTKNDDRCISVLNPAKFEQKSTESF----RCLVQRI------ 173
            ||           :.:|::|.||.|.|.:.|:. |:..:|.....|.:    :||...:
pombe   132 RTHSRSSSYFAVKSTIDRVRGDFNTGNINHCVR-LDYVRFGTPDAEGWNEFLKCLEWAVLSSLDS 195

  Fly   174 RFLMLTSYNRNIVKYEELIRSKREKRNIEGWDFRQYFFMQEDLALIFEKLELPTEALIQYDELDA 238
            |||.|:...|:|..::..|.|          |:..:|..:|.||..|..|.|..|:|.|.:::.:
pombe   196 RFLQLSEQIRSIKLFDSSIFS----------DYLLFFLQKERLAASFFDLVLYRESLEQCEDMFS 250

  Fly   239 MFSQFITHTGLNEKQQWLNHF-------RKPLDAFHGICLTRADKFE-MRNKIRDEGVSLLEFRN 295
            ..|:.|  :.::.|::.::.:       :..|..|:...|....::. :.|.:.|...:|..|..
pombe   251 TLSKII--SAIDGKKENISKYLGEGSDAQPDLKDFNSSFLILGSRYNTLHNLLADGDFTLFHFTL 313

  Fly   296 YLFERQAYLLLTCNDIPEIAKRLLNFLFSTLREVELI------------KLECQEGALCCWEFVC 348
            :|..:...|.|..:|..:        .||||::..|.            .||    .:..:.:.|
pombe   314 FLLSKIILLNLKISDYEK--------AFSTLQQALLFLTSSFFNEFVQNNLE----IIAAFNYDC 366

  Fly   349 ALEVLQLCEQAMEPNELTCFQHCAPIWNLAKDKLYELGKLCGLLPGCTPTSEQLHIVVQLSSGIG 413
            ...:.:...:|:..|:......||.|...|:.:|..:.:...|:...:|.             :.
pombe   367 YTLLFKKITEAIHNNDTPIPLCCAKILLYARRQLTRMARWNNLIDDSSPL-------------LW 418

  Fly   414 DAPS----EQHQFLQATPQLRDRS--PNRKPKKSGAEQLKEALGSNQAFQKLYLELAELAISTYK 472
            ..||    |.|          |.|  .||      .::|.|.:.|..:|...|..|:..|:|.:|
pombe   419 REPSFPLIEHH----------DNSLLDNR------FQKLSETISSTSSFLSEYYRLSSEALSIFK 467

  Fly   473 ----HVTRLRSARLVGL------DLGNFYCAL----------NEP--HKAVGFFTDLLRELKAEN 515
                ..:.:.:|...||      |..|.|.:|          |:|  .|...|:.|||.:|:
pombe   468 AYKNRYSFVNTACDTGLAQYLLEDYENAYASLKNVDVQTAWSNDPLEEKWSKFYVDLLEKLE--- 529

  Fly   516 WHMLSSQTLLELANCYRKMGDSLAYTKTCSSISCCAELETLVRTFYFDEFLKSLKTLKTTLSAQP 580
                .....||.|:...| |....|.|.                       |.|:..|.|  |:.
pombe   530 ----KFDEALEFASAISK-GKVSIYNKN-----------------------KILELSKKT--AKS 564

  Fly   581 SIENANYCVLEDHFRILDIEVVNQKPII-QDDYILVQLKVESLYPRGVVAENVKLCYELEAS--- 641
            .:.|     |:|.|   .||:.:...:: .||.|.:....||........::|...|.|.:|
pombe   565 KVWN-----LDDFF---TIEIPHMMAVVPHDDGINLSFMCESKVFDLESVDSVTCNYVLSSSKNP 621

  Fly   642 -SLELAMENVSLTASPSTV-----------------KAKDT---------SSRLKVSLQLVYKQD 679
             :|...:.| |:|.....|                 |.||:         .|..::.:....|..
pombe   622 MNLLFTLHN-SITDGKLNVHCNDIIPGRYHLKTIVFKLKDSVLSFQKDCLHSNKQIEVLNPTKHS 685

  Fly   680 NRLH------------SAAVACDLPKSKQPVRRTSSTKRKLSPSVQADFTN----FVQAE----- 723
            |.|:            ....||......:...:.|.::.|||....:.|||    |:..|
pombe   686 NHLYILQSKISQQFQNDGIFACIPIMFGERFYKASCSEIKLSYIENSGFTNLEKSFLSEESHCGL 750

  Fly   724 ----------NIALQPGVNLIEMKAKATRVGCWQFKQLCISMSSLEFLSEQLPFMPATFEISTKP 778
                      ||...|||..:.:....|.|...:|      :.:|.::.|
pombe   751 ESKTDSLVIKNIQKVPGVAKLYIPLTNTPVEGNEF------LINLSYILE--------------- 794

  Fly   779 ASATLEFKTLI----AGIVQ-----------PISLNVSGGSFIFPPDAKITLRCSKNLRIRQARN 828
            :..|:.|..::    ||||:           |::..:    |:.....:..:.||.|...:..:.
pombe   795 SGQTVRFGKVLHIENAGIVEANCEKTNNMRDPLTSTI----FLHIQPKEPIIFCSWNCMRKTKQG 855

  Fly   829 TDDEAAYNDDQSFESTLQVPLVQFKSFEERRIPLEVLTDMPGRKVSKHHEHHI------ALNC-- 885
            |.|..       |:....:|::.         |::..|       |.|.:..:      ::||
pombe   856 TYDNV-------FDIPYNIPVLS---------PMDCFT-------SCHFDSDMSIDLKFSMNCLR 897

  Fly   886 ------------PWSRTELPIAVDFQPAMEATCRL-----HTCGTQKFLQVIMKGMEAHLL---- 929
                        .|.|.:........|.::..|:.     .|.||....:.|.|.....:|
pombe   898 LADVVFMKLCVNIWERFDFIDIEHIMPLLDHACQQISLSNITQGTVVLPEEIRKLNGKKILNSFF 962

  Fly   930 ------------LQHAQVKCDVPGVQLLDLNPESQQPIEIYKSLTVTYLYEIQVEPLKTEHELPV 982
                        :||.:.:.....::......|.::.:   |:|...:.....:.||..:.|:..
pombe   963 DNEELRNEFSEFIQHLESEVSFNSLRSFVQEFEKKERL---KNLPFYFSLHQTIGPLPFKDEMQS 1024

  Fly   983 VKVHFVIKYAS---LSQP-DVWRTY------------GCAFDLV----DYTT--LFKLQAQ---- 1021
            ..:.::.|...   |::| ::..|:            |.:|::.    .|||  ||....|
pombe  1025 TTIEYIWKIPQKVLLNKPTEITLTFLRSLTHSKKEKQGQSFEIFYNFPAYTTTILFAGPTQRKIV 1089

  Fly  1022 LEPNELCRLRTVCNMNLKITKVHENPYTDLMYEVLNDQNLWAVCGRSAGVVSMKDVDSHSISLDV 1086
            .|.|:......|..:.|                             :||.|.:.:|..||...|:
pombe  1090 WEKNQTTAQEQVTAVFL-----------------------------TAGRVMLPEVVVHSKDDDI 1125

  Fly  1087 MPLSTGFLPMPSIRLSKYTAGGKSKTD 1113
            ..|..          :|||..|:...|
pombe  1126 SILKN----------TKYTLVGRPLND 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIDL	NP_650431.1	TRAPPC10	978..1138	CDD:289361	30/162 (19%)
trs130	NP_588342.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1931
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003974
OrthoInspector	1	1.000	-	-		oto100826
orthoMCL	1	0.900	-	-		OOG6_104539
Panther	1	1.100	-	-	LDO	PTHR13251
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1753
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.840