DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sdr and drl

DIOPT Version :9

Sequence 1:	NP_001287331.1	Gene:	Sdr / 41809	FlyBaseID:	FBgn0038279	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_001260566.1	Gene:	drl / 44355	FlyBaseID:	FBgn0015380	Length:	645	Species:	Drosophila melanogaster

Alignment Length:	191	Identity:	41/191 - (21%)
Similarity:	65/191 - (34%)	Gaps:	56/191 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   703 SRNHDYRRKEFEKVINYEHLLSIKKDEEPT---RPPTTTPAPTNATLAKERLAAINYENYRLNSE 764
            |:.|........|..:::.|.:|......:   .|.|.|  ||.|||.:.      :..|....|
  Fly   271 SKRHPSNGVHLIKTSSFQRLPTISSTAHNSIYVCPSTIT--PTYATLTRP------FREYEHEPE 327

  Fly   765 KKQRDLQDLDQHKYTIR----------------------HALPKCQNSHASVVQQVEEKCVAEEP 807
            :..|.||:|...|..:|                      ..|.|....|||   |::...:.:|.
  Fly   328 EFNRRLQELTVQKCRVRLSCLVQEGNFGRIYRGTYNDCQEVLVKTVAQHAS---QLQVNLLLQES 389

  Fly   808 LSGYELPGTQHFYCLSQLEPETHYRITIRACVEGV-VNGCSTPAEAVIKTASIQ-LERFIK 866
            :..||   ..|...||.|               |: :...:||......|.|:: |:.|::
  Fly   390 MMLYE---ASHPNVLSVL---------------GISIEDYATPFVLYAATGSVRNLKSFLQ 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_001287331.1	Recep_L_domain	58..173	CDD:279382
		Furin-like	209..332	CDD:279142
		Recep_L_domain	347..461	CDD:279382
		FN3	491..578	CDD:214495
drl	NP_001260566.1	WIF	21..157	CDD:128745
		PTK_Ryk	336..606	CDD:270639	23/118 (19%)
		Pkinase_Tyr	343..599	CDD:285015	21/111 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455355
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930