Protein Alignment: Sdr and igf1r

• Sequence 1: NP_001287331.1
• Gene: Sdr
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_002933351.1
• Gene: igf1r
• XenbaseID: XB-GENE-484032
• Length: 1362
• Species: Xenopus tropicalis
• Alignment Length: 914
• Identity: 250/915 (27%)
• Similarity: 414/915 (45%)
• Gaps: 204/915 (22%)

  Fly    21 LILLFLGASSPVLASSDDQTACG-SLEI-NKIADLRKLQNCTHVVGHVRLAYVDLTDVSGNYSLD 83
            |:||.||.|:        ...|| :::| |.:.:|::|::|..:.|::::..:      .|...:
 Frog    19 LLLLCLGPSA--------GRVCGPNMDIRNDVRELKQLEDCVVIEGYLQILLI------SNAKAE 69

  Fly    84 SLAS----NVTEISDYLMVYRCTGLISLQSIFPRLRIIRGQELLFDQYSLVVYENRNLRELGLVE 144
            ...:    .:|.|:|||:::|.:||:||.::||.|.:|||: :||..|:||::|..:|:|:||..
 Frog    70 DFRNLRFPKLTVITDYLLLFRVSGLVSLSNLFPNLTVIRGR-VLFYNYALVIFEMTDLKEIGLYN 133

  Fly   145 LLRIQSGFIRVESNPLLCFVETVDWIYLMGNATRQHFSLKHNRPQSQC-----------PLCGSL 198
            |..|..|.:|:|.|..||:|.||||..:: :|...:: :..|:|..:|           .:|...
 Frog   134 LRNITRGAVRIEKNSELCYVSTVDWSLIL-DAVYNNY-IVGNKPPKECVDLCPGAREKMQICEKS 196

  Fly   199 SADFEFIRNSSERCWNVNTTQLRPQPPRLKDCPIACGLNGCDSAGKCCDHNCVTGCYSQN----C 259
            |.:.||    ::|||:....|        |.||..||...|....:||...|:..|.:.:    |
 Frog   197 SINNEF----ADRCWSDEHCQ--------KACPGVCGKRACTDNKECCHPECLGSCMAPDNDTAC 249

  Fly   260 SLCAN--YQGRMGCVNQCVA-SYELNKRRCIGHRECRELGRIP------LIRGYQCVKKCPG--- 312
            ..|.:  |:||  ||..|.. :|:....|||...||.::..:.      :|...:||.:||.
 Frog   250 VACHHYFYEGR--CVPTCPPNTYKFEGWRCITREECAKMHIVVNSLTPFIIHKGECVYECPSGFM 312

  Fly   313 -NQKEILV---AKGIIHCQVECNGDFH-VKSAADLEVLQDCVTINGSLTIELTNIK--EKIVDAL 370
             |:.:.:.   .:|  .|...|:.... :.|....::|:.|..:.|:|.:   ||:  :.|...|
 Frog   313 LNESQSMTCSPCEG--PCPKVCDEKMKTIDSVTSAQMLEGCTVLKGNLQL---NIRKGQNIASEL 372

  Fly   371 ENALASVKEITGYLKVIHSAQLMSLTFLQNLDAIRGDKLVENKYALYVVNNYHLEHIWP-PNHLV 434
            ||.|..::.:|||:|:.||..|:||:||::|..|.|::.:...|:.||.:|.:|:.:|. ..|.:
 Frog   373 ENFLGLIETVTGYVKIRHSHALVSLSFLKSLRYILGEEQMPGNYSFYVFDNNNLQQLWDWSKHNL 437

  Fly   435 IIQRGTLFFHLNPRLCYEKIHQLQGSLKSGENISVADVSPNSNGERVICGDAVRSLNPKVEDLNS 499
            .|:.|.:.|..|.:||..:|::::....:....:..|:|.::||....|...|         ||.
 Frog   438 TIKEGKIRFAFNSKLCASEIYRMEEVTGTKGRQTAEDISLSTNGNMASCESHV---------LNF 493

  Fly   500 TAV-----RIIL--------DYMDWEGMETLIGYSYHYKEAPVQNVTMYDGRHGCGHDNW-LMDV 550
            |::     ||..        ||.|      ||.::.:||||...|||.|||:..||.::| ::||
 Frog   494 TSIITSKNRIKFTWERYRPPDYRD------LISFTVYYKEALFHNVTEYDGQDACGSNSWNMVDV 552

  Fly   551 VPNQSRRH----VISGLKPYTQYAYFVKTLTRT---EYHIQIDAYSKIGYFQT---LPDRPSPVL 605
            ....|:..    ::.||||:||||.:||.:|.|   ..||. .|.|||.|.:|   :|..|..|:
 Frog   553 DLPASKESDPGILLQGLKPWTQYAIYVKAITLTMLESRHIH-GAKSKIIYIRTDAAVPSIPQDVI 616

  Fly   606 RIYGSSEISSQILLHWWPPRRPNGVIKNYFVTAEKYNATKEAKDKNYVNVELENAKDIDCECAGV 670
               .:|..|||:::.|..|.:|||.:..|.|..::
 Frog   617 ---SASNSSSQLVVKWNSPSQPNGNLSYYIVRWQQ------------------------------ 648

  Fly   671 LPYYSGPQPDDEDYYNKEQITYEDALPNLIYVSRNHDYRRKEFEKVINYEHLLSIKKDEEPTR-- 733
                   ||.|...| :....:.|.:||           ||.....|:.|.:..:.|.|..|.
 Frog   649 -------QPQDRHLY-QYNYCFRDKVPN-----------RKYANGTIDTEGVTELTKPEGNTGEK 694

  Fly   734 ------PPTTTPAPTNATLAKERLAAINYENYRLNS------EKKQRDLQDLDQHKYTIRHALPK 786
                  |.|..........|:.|..   :||:..||      .:::||:       :.:.::
 Frog   695 GHCCACPKTEAEKKAEKDEAEYRKV---FENFLHNSIFVPRPNRRRRDV-------FAVGNS--- 746

  Fly   787 CQNSHA--SVVQQVE-----EKCVAEEPLSGYELPGTQHFYCLSQLEPETHYRITIRAC-VEGVV 843
            .|.||.  :.|:...     ||...|.|....::...:....:|.|:|.|.|||.|.:| .|...
 Frog   747 TQTSHGKNTTVEDFSNFSDFEKEDVEYPFYETKIDYKRERTVISNLQPFTLYRIDIHSCNHEAEK 811

  Fly   844 NGCS 847
            .|||
 Frog   812 LGCS 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_001287331.1	Recep_L_domain	58..173	CDD:279382	42/119 (35%)
		Furin-like	209..332	CDD:279142	37/143 (26%)
		Recep_L_domain	347..461	CDD:279382	38/117 (32%)
		FN3	491..578	CDD:214495	37/105 (35%)
igf1r	XP_002933351.1	Recep_L_domain	50..162	CDD:279382	42/119 (35%)
		Furin-like	176..330	CDD:279142	41/170 (24%)
		FU	231..277	CDD:238021	14/48 (29%)
		Recep_L_domain	350..464	CDD:279382	38/117 (32%)
		FN3	492..604	CDD:238020	44/119 (37%)
		FN3	609..>653	CDD:238020	17/84 (20%)
		FN3	834..921	CDD:238020
		PTKc_InsR_like	992..1268	CDD:173625
		Pkinase_Tyr	999..1266	CDD:285015

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG4258
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D120934at33208
OrthoFinder	1	1.000				FOG0000777
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910