Protein Alignment: Nup93-2 and Nup93-1

• Sequence 1: NP_650404.1
• Gene: Nup93-2
• FlyBaseID: FBgn0038274
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: NP_572929.1
• Gene: Nup93-1
• FlyBaseID: FBgn0027537
• Length: 823
• Species: Drosophila melanogaster
• Alignment Length: 829
• Identity: 372/830 (45%)
• Similarity: 540/830 (65%)
• Gaps: 39/830 (5%)

  Fly     1 MDLNTLLQRAQNLNNDAKAECELPAVERTLQQVLRATTELHSRVTQTGCKEIQAHILLGSKGVDL 65
            |||..||::||.|.|:...:.|:|.||||:.|||:||.|.||||||.|..::|||||||||||||
  Fly     1 MDLMELLKQAQRLTNETNTDTEVPGVERTMSQVLQATKEFHSRVTQMGTNDLQAHILLGSKGVDL 65

  Fly    66 PKLNQKLEALSARKTFEPLDVKADTDVRTFLKNERENAILSVIEDTKKNISDSANKQRWASMNKV 130
            |||.||||:||||:||||:|...:|:|:.:|||||||||||||::|.::|..|..:|:|..:...
  Fly    66 PKLTQKLESLSARQTFEPIDPVTETNVQAYLKNERENAILSVIDETNRSIFKSVERQKWRCIYSE 130

  Fly   131 WNEEKTRLLDALIAPS-QNFIDLQRLPEPTIVNPLCQPRSCLDPLELVYAQELRHYNELLLKSSH 194
            |.|||..||:||:.|: |:|.|:|....||.:.....|.|.|:..|.:||:::..:|:.:: ...
  Fly   131 WGEEKEALLNALVGPNQQDFPDVQFQIVPTAMADEPTPYSQLNGHEQMYAEQIAIHNQSII-LGR 194

  Fly   195 RPNLVQKFAHLSQ-SFGDCRLTDMWTLLACVTQISEPLRS--DPIKSRQQRPEFVTYAKSYLERR 256
            ||||:...||:.| ||.|..:.:||.:|..:|.: .|:.|  ||||:||..|:||..|::|||||
  Fly   195 RPNLLSTLAHVVQDSFNDESVAEMWNVLQFMTAL-PPVSSTIDPIKNRQTSPQFVEQARTYLERR 258

  Fly   257 YRVFMCSQVGGSYAN-------NSYQLVVAYVNHRFRAQQTI-GLVDTVREIPLWPLVYYGLRCG 313
            ||.:|...:..:.|.       :.|.:|.:||....:.|:.: ||.|.....||||.|||.||.|
  Fly   259 YRTYMRKFIVANLAKARRGGIPSVYHMVRSYVGVTLQGQRALYGLHDVNNGQPLWPHVYYSLRSG 323

  Fly   314 AVKVAVEFLREAGSSHDEFAQLVADRNAGETN--SKIENQLRLQYANKIRNSTDAYKKAVYCILL 376
            .:..|..:|:|:|:..|....|...:|....|  .|:|.||:|:|.:::|..||.||||||.:||
  Fly   324 DMDAAALYLKESGTCPDLLTLLTLRKNGDRDNLMVKLEGQLKLEYNSRLRACTDPYKKAVYVVLL 388

  Fly   377 GCDVNEVHGEVAKTIDDFLWMRLAMIQPGDADN-------YGKLQSMILEQYGEKYFNARQQPYL 434
            .||.:..|.|:.::|||||||:|::::..|..:       :..|||:|||:|||.|||||::..|
  Fly   389 ACDPHFTHVELMRSIDDFLWMQLSILRRSDQSDSNTEQLTFSGLQSLILEKYGENYFNAREKAAL 453

  Fly   435 YFETLALTGQFEAAIEFLARQDENRAHAVHMAIALFELGLLGSARSVSQPLLSIDIKDPQPLRRL 499
            ||:.|.||||||||||||||.::||.||:||||||.|:.:||:.|||.|.|||.|..||:|::||
  Fly   454 YFQVLTLTGQFEAAIEFLARTEKNRTHAIHMAIALNEISMLGTPRSVEQSLLSSDPDDPKPMKRL 518

  Fly   500 NLTRLIRQYVQRFERTDTSEALHYYYTLRCLKDSKGR-NMFMACVCDLVVDSGVFDTTIFDLIFG 563
            ||.|||..|.:.||||||::||||||.||..|...|| |:.:.|||||:|:.  .|..:.:||||
  Fly   519 NLVRLIVMYTKCFERTDTTQALHYYYLLRNFKSENGRGNVMLTCVCDLLVEK--CDDEMLELIFG 581

  Fly   564 KRQSSDQNDVN-SGLFRQFECPEFDTRTMAAQVGDELAALGNFEMSARLYEMAGKYNLAVKHICI 627
            ....  :|.:. .|::.:|:..|.|..::|..|||||:..|::|::..||.:.|:.:.|::.:..
  Fly   582 TEDK--KNGLRYGGIYAEFQIHECDKYSLAEMVGDELSKRGDYELAIELYFIGGQLDKALRLVNS 644

  Fly   628 LMAQVVHLPTLGGSLRERLGQDAQRFNQLLASDSIDVEPKMKSSFVLLQDLLIFFNFYHDGKFNA 692
            |:|||||.||..||:|.|||....|.:..|.....|||.::..::.:|..::.||:.||:|...:
  Fly   645 LLAQVVHQPTQNGSVRNRLGDIINRLDAALVVRKSDVEVQVVVTYTVLTKVMKFFDHYHEGALRS 709

  Fly   693 ALDLLRQTQLVPNTLDDVDVVLGNVKQLSGEVIKVLPDVIVAAMEIAQKQYKQL----KAGSGSS 753
            ||::|....|:|.:..:||..:.|:|::..||||||||:::|:|:|..::|.:|    :..||..
  Fly   710 ALEILTNNHLIPASSLEVDECVTNIKRMGPEVIKVLPDILLASMDIVYQEYVKLMDSNETASGFF 774

  Fly   754 LE------QTQMQQLRQRAKALSNMAATMPYRLPNDTNKRLIELELDMH 796
            .|      :..::.||.||||.:||||::|||:|:.||:||::||:.||
  Fly   775 DESKCVNKEPAVKHLRDRAKAFTNMAASVPYRMPSTTNQRLVQLEILMH 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-2	NP_650404.1	DUF2461	178..>238	CDD:295279	23/63 (37%)
		Nic96	213..781	CDD:282017	254/599 (42%)
Nup93-1	NP_572929.1	Nic96	215..808	CDD:309288	254/598 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C308312632
eggNOG	1	0.900				E1_KOG2168
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I2199
Isobase	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D187731at2759
OrthoFinder	1	1.000				FOG0002843
orthoMCL	1	0.900				OOG5_129616
Panther	1	1.100			P	PTHR11225
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R780
	8	7.920