Protein Alignment: Nup93-2 and npp106

• Sequence 1: NP_650404.1
• Gene: Nup93-2
• FlyBaseID: FBgn0038274
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: NP_588422.1
• Gene: npp106
• PomBaseID: SPCC1739.14
• Length: 933
• Species: Schizosaccharomyces pombe
• Alignment Length: 941
• Identity: 185/942 (20%)
• Similarity: 365/942 (39%)
• Gaps: 211/942 (22%)

  Fly     3 LNTLLQRAQNLNNDAKAECELPAVERTLQQVLRATTELHSRVTQTGCKEIQAHILLGSKGVDLPK 67
            ::.|.:::|:|.. ...|.::|.::..|.|:......|.|:|..|...:.:||.||...|::..:
pombe    25 ISDLREKSQHLFG-VLLEPQVPVIQYGLNQLEEKARNLESKVLLTRDGDTKAHYLLAESGMNAEQ 88

  Fly    68 LNQKLEALSARKTFEPLDVKADT---DVRTFLKNERENAILSVIEDTKKNISDSANKQRWASMNK 129
            ..||:.::.....::.|::...:   ...|.|.| .:|.:.|:....:.|:.:.  :.|....|.
pombe    89 TRQKIYSIHIHSPWDQLELDKKSLYEQPHTKLYN-GQNVVASIENGYQSNVYEF--QLRLMKNNG 150

  Fly   130 V-WNEEKTRLLD---ALIAPSQNF---IDLQRLPEPTIVNPLCQPRSCLDPLELVYAQELRHYNE 187
            : |...||..::   .|:....|.   ..:.....|.:..||....|       |.:|.:|...|
pombe   151 IAWENTKTEFMEDVGKLLHSKDNSGLGTSISMSLRPNLARPLLTASS-------VKSQSVRSLRE 208

  Fly   188 L----------LLKSSHRPNLVQK------------FAHLSQSF-------GDCRLTD----MWT 219
            :          |.|.....|.:..            ||..:.||       .:.|:.:    :|:
pombe   209 VGSNLPIPTGSLTKIDGLNNQLSNDLTRSQTTNIFGFAEKASSFAAAVHKLNEARIRNQACHVWS 273

  Fly   220 LLACVTQISEPLRSDPI--------------KSRQQRPEF--------------------VTYAK 250
            |.|.|:|:   :.::.|              ::|....:|                    :..:.
pombe   274 LFASVSQM---VNTEVIQLFDAWSLLAHMIDETRYGMGDFEARHLALDSSSAALAVEKNCIEGSL 335

  Fly   251 SYLERRYRVFM---CSQVGGSYANNSYQLVVAYVNHRF--RAQQTIGLVDTVREIPLWPLVYYGL 310
            .|||.::...:   .|..|.....||.:.|:||...||  ........|..|.::|||.:::|.:
pombe   336 KYLENQFLSLIDLHLSDAGHITTVNSVEKVIAYSKLRFYKNGSWIKSTVSVVNDVPLWVVLFYLM 400

  Fly   311 RCGAVKVAVEFLREAGSSHDEFAQL----------VADRNAGETNSKIENQLRLQYANKIRNS-T 364
            |.|.:..|::|:   .:..|:|.:|          .|...:.....::.::|:.:|...::.: .
pombe   401 RSGQLDAALQFV---NTYSDDFEKLGRSFPLYFYSYAKNPSLPLPKQLRDRLQAEYGQLMKYAPE 462

  Fly   365 DAYKKAVYCILLGCDVNEVH-GEVAKTIDDFLWMRLAMIQPGDAD--------------NYGKLQ 414
            |.:|.|:|.:|..|:.:.|. .||..|.:|::|::|...:....|              |..:|:
pombe   463 DPFKHAIYKLLGNCEPHRVSLPEVCVTSEDYMWIQLMFCRVNQNDVIDSNGGQSTNSLFNLYQLE 527

  Fly   415 SMILEQYGEKYFNARQQ-PYLYFETLALTGQFEAAIEFLARQDENRAHAVHMAIALFELGLLGSA 478
            ..|: .:|.:|||.:.. |..||..|.:.|:||.||.||  .......|.|.|:|:...|||.:.
pombe   528 KKIV-AFGPRYFNPKNNTPTNYFLALLMCGEFERAISFL--HTNYPVEATHFAVAMAYYGLLRTK 589

  Fly   479 R-SVSQPLLSIDIKDPQPLRRLNLTRLIRQYVQRFERTDTSEALHYYYTLRCLKDSKGRNMFMAC 542
            . ..::.:|..:..|.    ::|..:||..|::..|..|.:..|.|   :.|:.....   :.||
pombe   590 NYEKNENILIYEADDV----KINFPQLIIAYLKHLEYVDAAVYLDY---IACIPLVPA---YQAC 644

  Fly   543 VCD----LVVDSGVFDTTIFDLIFGKRQSSDQNDVNSGLFRQF-ECPEFDTRTM-------AAQV 595
            ..:    |::.|..|...:.|:       ....:..:||...: ....||..::       |.:.
pombe   645 SINLTKILLLQSHEFSKFLGDI-------KPDTERTTGLLDLYLRLIPFDHDSLQKLYLEGAREA 702

  Fly   596 GDELAALGNFEMSARLYEMAGKYN----LAVKHICILMAQVVHLPTLGGSLRERLGQDAQRFNQL 656
            .|:    |.|..|..||.:.|.|:    :|:|:    ::|.:....| .|:..:..::....:.:
pombe   703 DDD----GRFGDSIILYHLLGDYDTVIGVAIKN----LSQSIVSRGL-WSIDSKESKNMHISSNV 758

  Fly   657 LASDSIDV-----------EPKM--------KSSFVLLQDLLIFFNFYHDGKFNAALDLLRQTQL 702
            :||::.|.           .||.        |.:..:|..::.....|...|::..|.|:....|
pombe   759 VASEAPDALAANLLAMYESNPKKSAKVSATNKKALKVLLKVVKVQKLYGQEKWDEVLQLIEHLDL 823

  Fly   703 VPNTLDDVDVVLGNVKQL-----------------SGEVIKVLPDVIVAAMEIAQKQYKQL-KAG 749
            :|  :::|.......:|:                 ..||:.|:|.::..:|...:..|:.: |..
pombe   824 LP--INEVQAEFEPNEQIPPISARLRRRAFEFSTFQDEVLSVIPSLMYISMSSIKALYRTISKLP 886

  Fly   750 SGSSLEQTQMQQLRQRAKALSNMAATMPYRL 780
            ..:...:.::|:|:.:...|...:..:..||
pombe   887 VVNEESKKKLQRLQFKGSMLVMFSTMIESRL 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-2	NP_650404.1	DUF2461	178..>238	CDD:295279	17/107 (16%)
		Nic96	213..781	CDD:282017	138/693 (20%)
npp106	NP_588422.1	Nic96	288..918	CDD:282017	131/665 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1310
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0002843
OrthoInspector	1	1.000				T133360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11225
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R780
TreeFam	1	0.960
	8	8.050