Protein Alignment su(Hw) and L

DIOPT Version :10

• Sequence 1: NP_524349.1
• Gene: su(Hw) / 41740
• FlyBaseID: FBgn0003567
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_001188929.1
• Gene: L / 36609
• FlyBaseID: FBgn0288433
• Length: 1366
• Species: Drosophila melanogaster
• Alignment Length: 1119
• Identity: 210/1119 - (18%)
• Similarity: 336/1119 - (30%)
• Gaps: 385/1119 - (34%)

  Fly     1 MSASKEGKE----KKGKLLGVEN--ISPPKDKRPATRMKLLNDVGAGEDSEASTTTTTSRTPSNK 59
            ||..|:.|.    |.|:....||  :..||:       :||:.....||:|..         ...
  Fly     1 MSRRKQAKPRACLKLGEKEDEENTGLLEPKE-------ELLSGDEDNEDNEGE---------DED 49

  Fly    60 QEKRGSVA-----GSRIKILNEEI--LGTPKTEKRGATKSTAPAASTVKILNEKKTPSATVTAVE 117
            :|....||     |.|.:::..|.  ...|..::..|..:.|......:...|.:.|...|.|.:
  Fly    50 EEVADEVAPEGGGGERPQLVPNESQQQSWPTADEPAAPAAVAKEEEAEEGSEELQHPRDEVVASD 114

  Fly   118 TTKIKTSPSKRKKMEHYVLQAVKSENTKADTTVTVVTEEDDTIDFILADDEE------------- 169
            .........|....|...:.|.:.|:.:.|..:..::.::|      .||||
  Fly   115 AAANANGHCKSSGHEEDAVDAEEPEDLELDDELLSLSGDED------YDDEELQSLDSFYSDMYS 173

  Fly   170 ----------VVPGRIENNN----------GQEIVVTEDDEDLGEDGDE---------------- 198
                      :..|.:..|:          |||...||...:.|.||::
  Fly   174 THTSSSYSPSISDGTMTPNSHHLIGAPTAAGQEDHPTEGKINGGADGEDLPKPKRLPHFHHHHHH 238

  Fly   199 ----------------------DGEDSSGKGNSSQTKIKEIV----------EHVCGKCYKTFRR 231
                                  .|..:.|....:.:|..::.          .:.|..|.|||.|
  Fly   239 HYHHQQALKIANKLRKINKEAKMGATAGGGATGAASKFDKLTGEGIKSRGDGSYQCQFCEKTFPR 303

  Fly   232 -------VQSLKKHLEF-CRYDSGY--HLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFH 286
                   |||..:||.| |.|.|..  |.|..|..|.|...|:
  Fly   304 LGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNER---------------------- 346

  Fly   287 LGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLALHEEQHKSR------- 344
              :..||.|..:|......:.|: .||.....|.||:||....:.|.|..|.::||..
  Fly   347 --NYKCPHCEAAFSRSDHLKIHM-KTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAG 408

  Fly   345 GKP---------------------------YACKICG------KDF---TRSYHLKRHQKYSSCS 373
            |.|                           ||..:..      .||   :||.|:..    ::.:
  Fly   409 GNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRMDFPKRSRSNHVGG----TTTT 469

  Fly   374 SNETDTMSCKVCDRV--FYRLDNLRSHLK---QHLGTQVVKKP-------EYMCHTCKNCFYSLS 426
            :..|..:.|..|.:|  |..|:.|.:||:   :...||.||.|       :..|..|...|.:::
  Fly   470 ATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQTQAVKTPVQEGEGFQLSCEYCTMKFGNIA 534

  Fly   427 TLNIHIR-THTGE-------------------------------KP------------------- 440
            .|..|:| ||...                               ||
  Fly   535 GLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESRPAEDDLPTD 599

  Fly   441 ----------------------------FDCDLCDKKFSALVALKKHRRYHTGE-KPYSCTVCNQ 476
                                        |.|:.|:.......:.:.|.:.|..| ....|..|..
  Fly   600 LSNNKRRPLTPNPQAQTPLAPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGM 664

  Fly   477 AFAVKEVLNRHMKRH---TGERPHKCDECGKSFIQATQLRTH--SKTHIRPFPCEQCDEKFKTEK 536
            :...:....||:..|   ||...:....|||||.::..|:.|  |:..:....|..|.|..::..
  Fly   665 SLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRM 729

  Fly   537 QLERHVKTHSRTKRPVFSCAECKRNFRTPALLKEHMDE----GKH-----------SPKQ---QR 583
            .::.|:......:..:..|:.|...||:.|....|:..    |.|           :|.|   .|
  Fly   730 AMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGATSSAPTNPLQCMFCR 794

  Fly   584 SSMRSAVKI-------MERTDCAICDKNFDSSDTLRRHIRTVHECDPDDIFGVEPHPSKRAKKDI 641
            :...|.:::       ..:..|..|.:.|.....|.||:::.|.       ||:       .|:.
  Fly   795 AVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHG-------GVK-------DKEA 845

  Fly   642 ESEEVVPVALNT-----SAGSLISSQTDGNGVVVREFLVDEG--DGAAQTITLENETYTILPLDG 699
            .|..:..:.:|.     :|.:..::.|:.|..::...:..:|  .||:               .|
  Fly   846 NSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGAS---------------GG 895

  Fly   700 AIEGEQLTDEAGVKPEAKK--EEAQVSPVVKKEQRKSLAASLAAAIADNLEESCSEDDFSGEILT 762
            |..|.......|..|.|.|  ...||.....|.|     .|...|:...|.:....:.::.:..:
  Fly   896 AGSGGGGAQSGGAPPSANKFYSPLQVDTNALKAQ-----TSPHPALMYGLSQRYLMEMYAAKSTS 955

  Fly   763 EEDIKLKENVGK----LIDMLVDPPILKKYGWPNAPEETVLCKVIENCGHDLTKGGENYA----- 818
            ...   .|.||.    .......||.      |||...|..|.:.|.  .||....|.::
  Fly   956 PSG---NEGVGNSQPPAPQATAPPPP------PNASTATFSCGMCER--QDLRSEAELHSHRKLA 1009

  Fly   819 -ELDYGSRMR-EYC 830
             .|..|..:| .||
  Fly  1010 HNLKTGVSLRCAYC 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
su(Hw)	NP_524349.1	C2H2 Zn finger	292..313	CDD:275368	5/20 (25%)
		COG5048	<312..517	CDD:227381	65/344 (19%)
		C2H2 Zn finger	321..341	CDD:275368	7/19 (37%)
		C2H2 Zn finger	350..368	CDD:275368	5/26 (19%)
		C2H2 Zn finger	382..402	CDD:275368	8/24 (33%)
		C2H2 Zn finger	415..435	CDD:275368	6/20 (30%)
		C2H2 Zn finger	443..463	CDD:275368	3/19 (16%)
		COG5048	<467..620	CDD:227381	37/182 (20%)
		C2H2 Zn finger	471..491	CDD:275368	4/19 (21%)
		C2H2 Zn finger	499..519	CDD:275368	8/21 (38%)
		C2H2 Zn finger	525..545	CDD:275368	4/19 (21%)
		C2H2 Zn finger	555..572	CDD:275368	5/16 (31%)
		C2H2 Zn finger	598..615	CDD:275371	5/16 (31%)
L	NP_001188929.1	C2H2 Zn finger	294..314	CDD:275368	8/19 (42%)
		C2H2 Zn finger	322..342	CDD:275368	7/19 (37%)
		COG5048	336..769	CDD:227381	85/461 (18%)
		C2H2 Zn finger	350..370	CDD:275368	5/20 (25%)
		C2H2 Zn finger	378..398	CDD:275368	7/19 (37%)
		C2H2 Zn finger	630..650	CDD:275368	3/19 (16%)
		C2H2 Zn finger	659..679	CDD:275368	4/19 (21%)
		C2H2 Zn finger	689..707	CDD:275368	6/17 (35%)
		C2H2 Zn finger	1020..1041	CDD:275368	2/4 (50%)
		C2H2 Zn finger	1049..1069	CDD:275368
		C2H2 Zn finger	1197..1217	CDD:275368
		C2H2 Zn finger	1229..1246	CDD:275368
		C2H2 Zn finger	1258..1278	CDD:275368