DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	435	Identity:	111/435 - (25%)
Similarity:	176/435 - (40%)	Gaps:	82/435 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 IRYRVDFPIPTIPPKITSMQLNGVQLCSGGVYPKPRTGITLRITWTPSYISVF-GVNPQPVPTRP 158
            |:|:.  |:.:.|  |.:::.:||..|.   ......| .:|..|..|.:.|: |.:.:.:|. .
Mouse   189 IKYKE--PLESCP--IHAVRCDGVVDCK---MKSDELG-CVRFDWDKSLLKVYSGSSGEWLPV-C 244

  Fly   159 RPAWQDESPQIDYRETRPSQPRLEDSGELFGRSNESLPAFQNPGWGTAPQQAN-PNRGITSQPEI 222
            ..:|.|                           .:|....|..|:.:|.:... .:|.|||...:
Mouse   245 SSSWND---------------------------TDSKRTCQQLGFDSAYRTTEVAHRDITSSFLL 282

  Fly   223 PSPVPQRPTPNPSRSNAPQQAVRSPVDLVPQQNPSSNGIP-----CGRERASTTPLIFQGKSLQR 282
                        |..|...|.     .|...|.||...:.     ||. ||.|..:: .|.....
Mouse   283 ------------SEYNTTIQE-----SLYRSQCPSRRYVSLQCSHCGL-RAMTGRIV-GGALTSE 328

  Fly   283 GQLPWLVAIFERRESNGPAFICGGTLISTSTVLSAAHCFRAPGRDLPASRLAVSLGRNTLAIHSD 347
            .:.||.|::     ..|...|||||||....||:|||||... |:.......|..|.:.|  |..
Mouse   329 SKWPWQVSL-----HFGTTHICGGTLIDAQWVLTAAHCFFVT-REKLLEGWKVYAGTSNL--HQL 385

  Fly   348 GEFRGVSQLIIHENFQFKQFTEADLALVRLDEPVRYTDYIVPICLWSTSNRMDLPQGLKSYVAGW 412
            .|...:||:||:.|:..:| .:.|:||:||.:|:..:.:|.|.||........|.:  ..::.|:
Mouse   386 PEAASISQIIINGNYTDEQ-DDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLNE--TCWITGF 447

  Fly   413 G-PDETGTGNTEVSKVTDLNIVSEANCALELPH-VLVQPSSLCA--KKTGAGPCASDGGGPLMLR 473
            | ..||....:...:...:|::....|...|.: ..:.|..:||  .:.|...|..|.||||:..
Mouse   448 GKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCE 512

  Fly   474 EQDVWVLRGVISGGVINEKENTCELSKPSVFTDVAKHIEWVRQKM 518
            :.:.|.|.||.|.|....::|     ||.|:|.|.:.:.|:.:||
Mouse   513 QNNRWYLAGVTSWGTGCGQKN-----KPGVYTKVTEVLPWIYRKM 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649	8/30 (27%)
		Tryp_SPc	277..517	CDD:238113	72/243 (30%)
		Tryp_SPc	277..514	CDD:214473	71/240 (30%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060	4/19 (21%)
		SRCR_2	225..314	CDD:373897	24/134 (18%)
		Tryp_SPc	319..548	CDD:214473	71/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910