DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and AgaP_AGAP001707

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_321381.5	Gene:	AgaP_AGAP001707 / 1281466	VectorBaseID:	AGAP001707	Length:	511	Species:	Anopheles gambiae

Alignment Length:	531	Identity:	148/531 - (27%)
Similarity:	236/531 - (44%)	Gaps:	83/531 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLLLASLINL-VLGQLPRNGCSGRFQYQ---------GY---QGQYIG-LVEVRHPEANNQTLIL 59
            :|||..|.:. |.||..|:.|...|.|:         ||   ||..|| ||::      |..|.:
Mosquito    32 LLLLGPLAHSPVEGQYLRSPCPDVFSYRLDPGTNQVFGYVELQGLRIGQLVKL------NVDLSI 90

  Fly    60 QFSQQGYHDFEDYVGSISLVDDDEVTQENLRQGLPIRYRVDFPIPTIPPKITSMQLNGVQLCSGG 124
            ..:..     ::.||||:||...|.|..::....|.:|||:||...:.|.:.::.:||..:|:|
Mosquito    91 AIAVP-----QNNVGSITLVKSREETFRDIYSNQPAQYRVNFPFNNVIPSVLAISVNGQTICTG- 149

  Fly   125 VYPKPRTG---ITLRITWTPSYISVFGVNPQPVPTRPRPAWQDESPQIDYRETRPSQPRLEDSGE 186
               :..||   .|:.:..|     :|        |:.:|                    |.:||
Mosquito   150 ---QKATGNIVTTINLEHT-----LF--------TQMQP--------------------LANSG- 177

  Fly   187 LFGRSNESLPAFQNPGWGTAPQQANPNRGITSQPEIPSPVPQRPTPNPSRSNAPQ--QAVRSPVD 249
                :|.:...|| |...|| .||...|.:..|..:..|.|| |.|.|.::..||  |..|..||
Mosquito   178 ----NNINAIQFQ-PQQNTA-VQAPVYRPVQQQQPVVQPQPQ-PRPRPVQTPRPQPVQTQRPSVD 235

  Fly   250 LVPQQNPSSNGIPCGRERASTTPLIFQGKSLQRGQLPWLVAIFERRESNGPAFICGGTLISTSTV 314
            ....:...|..|.||:..|....|...|....:||.||...||:......|.:|||.|:|....:
Mosquito   236 FSSTEAGGSASIGCGQPAAVFNRLSINGIRSPKGQFPWAAPIFDTGVPAKPKYICGSTIIGERHL 300

  Fly   315 LSAAHC-FRAPGRDLPASRLAVSLGRNTLAIHSDGEF--RGVSQLIIHENFQFKQ--FTEADLAL 374
            ::|||| :.:.|....|:.|....|.:.:....|.:.  |.|.::.|||::.|:.  ..:.|:|:
Mosquito   301 VTAAHCMYDSIGNPRSANDLTTVPGMHNIDNFFDADLQERSVKKIFIHEDYYFEDSILLDTDIAV 365

  Fly   375 VRLDEPVRYTDYIVPICLWSTSNRMDLPQGLKSYVAGWGPDETGTGNTEVSKVTDLNIVSEANCA 439
            :.:|:|:.|.:.:.|||||..|:.::...|.|.:|:|||..|  .||.:........:|....|.
Mosquito   366 MLIDQPLTYNNLVRPICLWQESDNLEQIVGQKGFVSGWGVTE--DGNAKYPSYVTATVVDRRTCT 428

  Fly   440 LELPHVLVQPSSL-CAKKTGAGPCASDGGGPLMLREQDVWVLRGVISGGVINEKENTCELSKPSV 503
            ..|..::...:.: ||...|:.||..|.|..|:::....:.:||::|.|..:....||...|..:
Mosquito   429 RNLERLIAGNARIFCADGHGSVPCTGDSGSGLVIKRGSRYYIRGIVSVGQYDPNTLTCARDKYVL 493

  Fly   504 FTDVAKHIEWV 514
            :||:|....|:
Mosquito   494 YTDIAPFRYWL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649	32/112 (29%)
		Tryp_SPc	277..517	CDD:238113	70/244 (29%)
		Tryp_SPc	277..514	CDD:214473	69/242 (29%)
AgaP_AGAP001707	XP_321381.5	GD_N	50..150	CDD:292649	32/114 (28%)
		Tryp_SPc	261..507	CDD:238113	70/246 (28%)
		Tryp_SPc	261..503	CDD:214473	69/243 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BPFK
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	186	1.000	Inparanoid score	I6368
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.830