DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and F11

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	409	Identity:	110/409 - (26%)
Similarity:	168/409 - (41%)	Gaps:	85/409 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 AWQDESPQ----IDYRETRPSQPRLEDSGELFGRS----NESLPAFQNPGWGTAPQQANPNRGIT 217
            ||..||.:    :...|:.....|:..|..|.|.|    ..|:|.|.:|.:      .|....:.
Mouse   245 AWPKESQRHLCLLKTSESGLPSTRITKSHALSGFSLQHCRHSVPVFCHPSF------YNDTDFLG 303

  Fly   218 SQPEIPSPVPQRPTPNPSRSNA--------PQQAVRSPVDLVPQQNP--------SSNGIP---- 262
            .:.:|.....|........:||        |...      |..::|.        ||||.|
Mouse   304 EELDIVDVKGQETCQKTCTNNARCQFFTYYPSHR------LCNERNRRGRCYLKLSSNGSPTRIL 362

  Fly   263 -------------CGRERASTT---PLIFQGKSLQRGQLPWLVAIFERRESNGPAFICGGTLIST 311
                         |..:...||   |.:..|.:...|:.||.|.:   ..|.|  .:|||::|..
Mouse   363 HGRGGISGYSLRLCKMDNVCTTKINPRVVGGAASVHGEWPWQVTL---HISQG--HLCGGSIIGN 422

  Fly   312 STVLSAAHCFRAPGRDLPASRLAVSLG-RNTLAIHSDGEFRGVSQLIIHENFQFKQFTEA----D 371
            ..:|:|||||  .|.:.| .:|.|..| .|...|:....|..|.::|||:     |:|.|    |
Mouse   423 QWILTAAHCF--SGIETP-KKLRVYGGIVNQSEINEGTAFFRVQEMIIHD-----QYTTAESGYD 479

  Fly   372 LALVRLDEPVRYTDYIVPICLWSTSNRMDLPQGLKSYVAGWGPDE-TGTGNTEVSKVTDLNIVSE 435
            :||::|:..:.|||:..||||.|..:|..:  ..:.:|.|||... .|...:.:.| ..:.:||.
Mouse   480 IALLKLESAMNYTDFQRPICLPSKGDRNAV--HTECWVTGWGYTALRGEVQSTLQK-AKVPLVSN 541

  Fly   436 ANCALELPHVLVQPSSLCA--KKTGAGPCASDGGGPLMLREQDVWVLRGVISGGVINEKENTCEL 498
            ..|........:....:||  |:.|...|..|.||||..:...||.|.|:.|.|     |...:.
Mouse   542 EECQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYNGVWHLVGITSWG-----EGCGQK 601

  Fly   499 SKPSVFTDVAKHIEWVRQK 517
            .:|.|:|:|||:::|:.:|
Mouse   602 ERPGVYTNVAKYVDWILEK 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	78/247 (32%)
		Tryp_SPc	277..514	CDD:214473	77/244 (32%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519	10/37 (27%)
		APPLE	291..376	CDD:128519	14/96 (15%)
		Tryp_SPc	389..617	CDD:214473	77/248 (31%)
		Tryp_SPc	390..617	CDD:238113	77/247 (31%)
		Heparin-binding. /evidence=ECO:0000250	547..550		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910