Protein Alignment Abi and Abi2

DIOPT Version :10

• Sequence 1: NP_001247091.1
• Gene: Abi / 41718
• FlyBaseID: FBgn0020510
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001391634.1
• Gene: Abi2 / 329165
• MGIID: 106913
• Length: 542
• Species: Mus musculus
• Alignment Length: 581
• Identity: 227/581 - (39%)
• Similarity: 294/581 - (50%)
• Gaps: 165/581 - (28%)

  Fly    13 MDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQI 77
            |.||..|:..|||.||::|.||||||||||||||:.|.::.:|:.|||.||.|||||||||||.|
Mouse     1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLI 65

  Fly    78 NTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINP 142
            ||||.:.:|:|::||.||..|||.:|||:|||.||||||||||||:||.||.:||..||:||.|.
Mouse    66 NTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANL 130

  Fly   143 EKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSL----LPPSVGPPPTTKPPT 203
            |:|::|:||||||::||:||||:......:|          |.|::    ||.:.  |||.|||:
Mouse   131 ERPVRYIRKPIDYTILDDIGHGVKWLLRFKV----------STQNMKMGGLPRTT--PPTQKPPS 183

  Fly   204 PPQMSRAGNTGTLGKSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGH-------PKRMS 261
            ||              :|..||||:.| .|||...|.||.||:.|.|: |..:       |.|.:
Mouse   184 PP--------------MSGKGTLGRHS-PYRTLEPVRPPVVPNDYVPS-PTRNMAPSQQSPVRTA 232

  Fly   262 TASSTMTTTTTGGGAAGNERAAGYSA----------------LPMPPS------------QQIAT 298
            :.:....|.::.|.:.|:..::..|:                .|.|||            ...||
Mouse   233 SVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPAT 297

  Fly   299 HVNLP----------------SAGMMQSL-----PPPPPTTYDDRSSMPP--------------- 327
            ..::|                :||..|||     .|.||..    ||.||
Mouse   298 SASVPTPLVPATVPSSTAPDAAAGGAQSLADGFTSPTPPVI----SSNPPTGHPVQFYSMNRPAS 358

  Fly   328 --APPS----------PLTVSQHEMTEQSHIGMHTLGRNINRNP--NRNHFSLNFARPG------ 372
              .||:          |...||..:..|           :|..|  |:|..||....|.
Mouse   359 RHTPPTIGGSLPYRRPPSITSQTSLQNQ-----------MNGGPFYNQNPVSLAPPPPSILQVTP 412

  Fly   373 ---------------SQSPPLPPP---------PPPEDEHQDFGRPRTSTGPQLAPIVPEDQNLP 413
                           |.:||.|||         |||....:|:.....:......|...||   |
Mouse   413 QLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEED---P 474

  Fly   414 GWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVE 474
            .|.|:.::|||||||||..||:|||||||.:::||:|||||||:||||:||||||||||||
Mouse   475 PWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abi	NP_001247091.1	Abi_HHR	105..168	CDD:462279	42/62 (68%)
		SH3_Abi	423..474	CDD:212760	40/50 (80%)
Abi2	NP_001391634.1	Abi_HHR	93..156	CDD:462279	42/62 (68%)
		PHA03247	<270..406	CDD:223021	31/150 (21%)
		SH3_Abi2	481..541	CDD:212905	43/55 (78%)