Protein Alignment Abi and abi-1

DIOPT Version :10

• Sequence 1: NP_001247091.1
• Gene: Abi / 41718
• FlyBaseID: FBgn0020510
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_498224.1
• Gene: abi-1 / 175789
• WormBaseID: WBGene00015146
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 177/541 - (32%)
• Similarity: 252/541 - (46%)
• Gaps: 153/541 - (28%)

  Fly    13 MDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQI 77
            :::|..||...|||.|..|..|:.||::||.||||.|.:::||.||||.:|.:..|:||||||||
 Worm     3 VNDLQELIERRIPDNRAQLETSHANLQQVAAYCEDNYIQSNNKSAALEESKKFAIQALASVAYQI 67

  Fly    78 NTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINP 142
            |.:......:|.||..::..:.:|:.:::|.|.:||||:||||||.||.||...:|.||:||..|
 Worm    68 NKMVTDLHDMLALQTDKVNSLTNQVQYVSQVVDVHKEKLARREIGSLTTNKTLFKQPKIIAPAIP 132

  Fly   143 EKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSLLPPSVGPPPTTKPPTPPQM 207
            ::..:|.|.|||:|:||.||||:.                               |:.||....:
 Worm   133 DEKQRYQRTPIDFSVLDGIGHGVR-------------------------------TSDPPRAAPI 166

  Fly   208 SRAGNTGTLGKSVS---------------NTGTLGKSSR---------EYRTPPVVNPPQVPSHY 248
            ||| .:...|.|.|               .|.|||::.|         :||.|.|.  ||..|.
 Worm   167 SRA-TSSISGSSPSQFHNESPAYGVYAGERTATLGRTMRPYAPSIAPSDYRLPQVT--PQSESR- 227

  Fly   249 APNYPIGHPKRMSTASSTMTTTTTGGGAAGNERAAGYSALPMPP---------SQQIATHVNLP- 303
                 ||  ::||..|......:.|||:.....::.|:::..|.         ...:....::|
 Worm   228 -----IG--RQMSHGSEFGDHMSGGGGSGSQHGSSDYNSIYQPDRYGTIRAGGRTTVDGSFSIPR 285

  Fly   304 ------SAGMMQS--LPPPPP----TTYDDRSSMPPAPPSPLTVSQHEMTEQSHIGMHTLGRN-I 355
                  |||..:|  .|.|||    |.|       .||.|.:...|.:..:|.:.|  |:.:: :
 Worm   286 LSSAQSSAGGPESPTFPLPPPAMNYTGY-------VAPGSVVQQQQQQQMQQQNYG--TIRKSTV 341

  Fly   356 NRNPNRNHFSLNFARPGSQSPPLPPPP-----------PPEDEHQDFGRPRTSTG---------- 399
            ||:                  .|||||           |.:|:..|...|..|.|
 Worm   342 NRH------------------DLPPPPNSLLTGMSSRMPTQDDMDDLPPPPESVGGSSAYGVFAG 388

  Fly   400 ----------PQLAPIVPEDQNLPGWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDD 454
                      |.|.      ....||:|..::|||..:|||.|.|:|||:.:|::::||||||||
 Worm   389 RTESYSSSQPPSLF------DTSAGWMPNEYLEKVRVLYDYDAAKEDELTLRENAIVYVLKKNDD 447

  Fly   455 GWWEGVMDGVTGLFPGNYVEP 475
            .|:|||:||||||||||||.|
 Worm   448 DWYEGVLDGVTGLFPGNYVVP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abi	NP_001247091.1	Abi_HHR	105..168	CDD:462279	34/62 (55%)
		SH3_Abi	423..474	CDD:212760	34/50 (68%)
abi-1	NP_498224.1	Abi_HHR	95..158	CDD:462279	34/93 (37%)
		SH3_Abi	416..466	CDD:212760	33/49 (67%)