Protein Alignment Abi and Abi1

DIOPT Version :10

• Sequence 1: NP_001247091.1
• Gene: Abi / 41718
• FlyBaseID: FBgn0020510
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001070658.1
• Gene: Abi1 / 11308
• MGIID: 104913
• Length: 481
• Species: Mus musculus
• Alignment Length: 537
• Identity: 219/537 - (40%)
• Similarity: 283/537 - (52%)
• Gaps: 138/537 - (25%)

  Fly    13 MDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQI 77
            |.||..|:..|||.|:::|.:||.||.|||||||:.|.:|.:|:.|||.||.|||||||||||||
Mouse     1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQI 65

  Fly    78 NTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINP 142
            |.||.:.:|||::||.||..|||.:|||:|||.||||||||||||:||.||.:||..||:||.|.
Mouse    66 NALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANM 130

  Fly   143 EKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSLLPPSVGP-----PPTTKPP 202
            |:|::|:||||||::||::|||:          |...:.||:.|   |...|.     |||.|||
Mouse   131 ERPVRYIRKPIDYTVLDDVGHGV----------KWLKAKHGNNQ---PARTGTLSRTNPPTQKPP 182

  Fly   203 TPPQMSRAGNTGTLGKSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGHPKRMS------ 261
            :||              ||..||||::: .|:|...|.||.||:.|..:     |.|:.
Mouse   183 SPP--------------VSGRGTLGRNT-PYKTLEPVKPPTVPNDYMTS-----PARLGSQHSPG 227

  Fly   262 -TASSTMTTTTTGG--GAAGNERAAGYSALPMPPSQQIATHVNLPSAGMMQSLPPPPPTTYDDRS 323
             |||......|..|  |.:|:...:|.|::.:|        :.:|:        |.|||.
Mouse   228 RTASLNQRPRTHSGSSGGSGSRENSGSSSIGIP--------IAVPT--------PSPPTA----- 271

  Fly   324 SMPPAPPSPLTVSQH-EMTEQSHIGMH----------------------TLGRNINRNPNRNHFS 365
              .||.|.....||: .||.|  |..|                      :...::|..|..:..|
Mouse   272 --GPAAPGAAPGSQYGTMTRQ--ISRHNSTTSSTSSGGYRRTPSVAAQFSAQPHVNGGPLYSQNS 332

  Fly   366 LNFARPGSQSP----------------------PLPPPPPPEDE---HQDFGRPRTSTGPQLAPI 405
            ::.|.|....|                      |.||||||.|:   ..|...|     |...|:
Mouse   333 ISVAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP-----PPPPPV 392

  Fly   406 VPEDQNL-------------PGWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWW 457
            ..||:..             |.|.|||:||||||||||..||||||||:|.:::||:|||||||:
Mouse   393 DYEDEEAAVVQYSDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWF 457

  Fly   458 EGVMDGVTGLFPGNYVE 474
            |||.:.|||||||||||
Mouse   458 EGVCNRVTGLFPGNYVE 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abi	NP_001247091.1	Abi_HHR	105..168	CDD:462279	41/62 (66%)
		SH3_Abi	423..474	CDD:212760	38/50 (76%)
Abi1	NP_001070658.1	Required for binding to WASF1	18..79		39/60 (65%)
		Abi_HHR	93..156	CDD:462279	42/72 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..285		49/172 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..348		6/29 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	361..392		11/35 (31%)
		SH3_Abi1	423..481	CDD:212904	40/52 (77%)