Protein Alignment ems and nkx6.1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Alignment Length: 332
• Identity: 91/332 - (27%)
• Similarity: 131/332 - (39%)
• Gaps: 78/332 - (23%)

  Fly   171 PQMAV--SLKRERSPAPPAME-QAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQ 232
            |.:|.  |:...::|..||.. .:..||....|..|.|.    ....|.|||.:..||..:....
Zfish    20 PPLAALHSMTEMKTPLYPAYPLSSTGPASSTSPTATSPN----PGGIPVSSPGIKTSSGLSALAS 80

  Fly   233 QQQQQPPPNYPKPAMMHPGGAGPMM-MPGM--PPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPP 294
            .||         .|:..|.|...:: .|.:  .|||::                .|||...:|.|
Zfish    81 AQQ---------CAIATPHGINDILSRPSVACSPAGIL----------------SGLPRFSSLSP 120

  Fly   295 YINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPN------PGM 353
                ||  ||                    |....|:|||.|.|..|....: :|.      ||:
Zfish   121 ----PP--PP--------------------GLYFSPSAAAVAVARYPKPLTE-LPGRTPIFWPGV 158

  Fly   354 ARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAER 418
            .:..:    |..:|.. ..||:  .|.|:....|.|..|..||..|:..||..||..:|:.|.||
Zfish   159 MQSPH----WRDARFA-CSPHQ--NSVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPER 216

  Fly   419 KALAQNLNLSETQVKVWFQNRRTKHKR---MQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMD 480
            ..||.:|.::|:||||||||||||.::   .:....|..:......:...|.:||||:..:..:|
Zfish   217 ARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGASENEDDDDDYNKPLD 281

  Fly   481 ECPSDEE 487
            ....||:
Zfish   282 PNSDDEK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	30/57 (53%)