Protein Alignment ems and cdx1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 282
• Identity: 66/282 - (23%)
• Similarity: 96/282 - (34%)
• Gaps: 107/282 - (37%)

  Fly   183 PAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAM 247
            ||||  :.::.|:..    |.|..:..|...||..:.:      ..||.::.
 Frog    32 PAPP--QYSDFPSYH----HVPGINSDPHHGQPGGTWS------SYTPSRED------------- 71

  Fly   248 MHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIA 312
            .||.|.||......|......|....|..||    .|||     |||.:|
 Frog    72 WHPYGPGPGASSANPAQISFSPSDYNPVQPP----GPGL-----LPPSLN--------------- 112

  Fly   313 AAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFP 377
                                  ::.:.|.|.|.:           ..||.| :.|.|
 Frog   113 ----------------------SSVSPLSPSAQR-----------RNLYEW-MRRTG-------- 135

  Fly   378 GSFLVP-------PFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVW 435
                ||       ..|...:.|..::..|.|:||..|..::|:....:..||.:|.|:|.|||:|
 Frog   136 ----VPTSTNSNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLALTERQVKIW 196

  Fly   436 FQNRRTKH-----KRMQQEDEK 452
            |||||.|.     |:|||:.::
 Frog   197 FQNRRAKERKVNKKKMQQQSQQ 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	22/60 (37%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	39/203 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		25/146 (17%)
		Homeodomain	151..206	CDD:459649	22/54 (41%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		6/20 (30%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		8/10 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		5/16 (31%)