Protein Alignment ems and HMX3

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001099044.1
• Gene: HMX3 / 340784
• HGNCID: 5019
• Length: 357
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 90/320 - (28%)
• Similarity: 123/320 - (38%)
• Gaps: 99/320 - (30%)

  Fly   186 PAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPN--------- 241
            |..:.|...:.:.|||  ||...:|:.| |.|...||....|..||   :.||||.
Human     4 PGPDAAGTASAQPQPP--PPPPPAPKES-PFSIKNLLNGDHHRPPP---KPQPPPRTLFAPASAA 62

  Fly   242 ---------YPKPAMMHPGGAG----------------PMMMPGMPPAGLVR------PFPMGPG 275
                     ..|.|:  .|.||                |.....:|...|.|      |:.:.|.
Human    63 AAAAAAAAAAAKGAL--EGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPA 125

  Fly   276 GPPMPQGQPGLPDI--KAL---------------PPYINAPP---ELPPQHNPHLIAAAQFQMAA 320
            |..:|:     |:.  |||               .|.:.|.|   ||..:....:|........:
Human   126 GGHLPR-----PEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEES 185

  Fly   321 ALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPF 385
            ..:     |.||..||.|.:...||    .|| |.|      |   :.|...|.:.|..
Human   186 KKE-----GEAAPGAAGASVGAAAA----TPG-AED------W---KKGAESPEKKPAC------ 225

  Fly   386 RKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKR 445
             :.|:.||.||.||:.:||..|:..:|:..:||..||.:|:|:|||||:||||||.|.||
Human   226 -RKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKR 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
HMX3	NP_001099044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		20/59 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..229		27/130 (21%)
		Homeodomain	228..284	CDD:459649	29/55 (53%)