Protein Alignment ems and HOXB7

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 60/205 - (29%)
• Similarity: 87/205 - (42%)
• Gaps: 60/205 - (29%)

  Fly   304 PQHNPHLIAAAQFQMAAALQ-----AGHVLGPAAAA--AAAAGLPP-----HAAQFMPN-----P 351
            || .|...|.:....||::|     .|.:.|.:||.  ||..||.|     |.|.|..|     |
Human    38 PQ-RPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCP 101

  Fly   352 G----------------MARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQL 400
            |                .|..::::|||:          |..|:       ..||.|..::..|.
Human   102 GDSAKAAGAKEQRDSDLAAESNFRIYPWM----------RSSGT-------DRKRGRQTYTRYQT 149

  Fly   401 LKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEG--GSQRNMH 463
            |:||..|..|:|:....|..:|..|.|:|.|:|:||||||.|.|:   |::..|.|  |..|
Human   150 LELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKK---ENKTAGPGTTGQDR--- 208

  Fly   464 NGSGDEDDDE 473
             ...:|:::|
Human   209 -AEAEEEEEE 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		3/14 (21%)
		Homeodomain	138..194	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		6/29 (21%)