Protein Alignment ems and HOXB2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 72/252 - (28%)
• Similarity: 96/252 - (38%)
• Gaps: 70/252 - (27%)

  Fly   212 SSQPS------SSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPF 270
            :||||      |.|.:|.:...::..:.....|||.:.:        ..|.:.||.......|..
Human    13 NSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQ--------TFPSLQPGASTLQRPRSQ 69

  Fly   271 PMGPGGPPMPQGQPGLPDIKALPPYINAPPELP------PQHNPHLIAAAQFQMAAALQAGHVLG 329
            .....||.:|...|  |.:.|.||    .||.|      ....|...|.:....|:|:.|..|..
Human    70 KRAEDGPALPPPPP--PPLPAAPP----APEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGS 128

  Fly   330 PAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTA 394
            |    |...|||....      |.||                                  |:|||
Human   129 P----ADGLGLPEAGG------GGAR----------------------------------RLRTA 149

  Fly   395 FSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDE 451
            ::.:|||:||..|..|:|:....|..:|..|:|:|.||||||||||.||||..|..|
Human   150 YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHRE 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		29/126 (23%)
		Antp-type hexapeptide	94..99		2/4 (50%)
		Homeodomain	144..200	CDD:459649	30/89 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		6/10 (60%)