Protein Alignment ems and Tlx1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_006526978.1
• Gene: Tlx1 / 21908
• MGIID: 98769
• Length: 345
• Species: Mus musculus
• Alignment Length: 220
• Identity: 68/220 - (30%)
• Similarity: 94/220 - (42%)
• Gaps: 57/220 - (25%)

  Fly   273 GPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAA-----------AQFQMAAALQAGH 326
            |||||..|.|..|  ...::.|       ||..:|.::..|           .....|.||.|..
Mouse    78 GPGGPGGPAGGGG--GACSMGP-------LPGSYNVNMALAGGPGPGGGGGGGGAGGAGALSAAG 133

  Fly   327 VL-----GPAAAAAA-----AAGLPPHAAQFMPN----PGMARDSYQLYPWLLSRHGRIFPHRF- 376
            |:     .|.|.|.|     |.|||.     :|:    ||:...:...:||:.|.. |....||
Mouse   134 VIRVPAHRPLAGAVAHPQPLATGLPT-----VPSVPAVPGVNNLTGLTFPWMESNR-RYTKDRFT 192

  Fly   377 --------------PGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNL 427
                          |.....||  |.|:.||:|:..|:.:||..|...:|:..|||.|||:.|.:
Mouse   193 VALSPFTVTRRIGHPYQNRTPP--KKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM 255

  Fly   428 SETQVKVWFQNRRTKHKRMQQEDEK 452
            ::.|||.||||||||.:|...|:.:
Mouse   256 TDAQVKTWFQNRRTKWRRQTAEERE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
Tlx1	XP_006526978.1	Homeodomain	217..273	CDD:459649	27/55 (49%)