Protein Alignment ems and Nkx3-1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_035051.1
• Gene: Nkx3-1 / 18095
• MGIID: 97352
• Length: 237
• Species: Mus musculus
• Alignment Length: 236
• Identity: 66/236 - (27%)
• Similarity: 88/236 - (37%)
• Gaps: 70/236 - (29%)

  Fly   225 SPHATPPQQQQQQP----PPNYPKPAMMHPGGAG-PMMMPGMPPAGLVRPFPMGPGGPPMPQGQP 284
            ||.|.||.|.::..    .......|..|.|.:| |...|  .|.....|.|...||..:....|
Mouse    18 SPWAAPPTQSKRLTSFLIQDILRDRAERHGGHSGNPQHSP--DPRRDSAPEPDKAGGRGVAPEDP 80

  Fly   285 GLPDIKALPPYINAPPELP--PQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQF 347
              |.|:      ::|.|.|  |:.:.|      |: ...|...|..|..|:|......|
Mouse    81 --PSIR------HSPAETPTEPESDAH------FE-TYLLDCEHNPGDLASAPQVTKQP------ 124

  Fly   348 MPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQY 412
                                                    .||.|.|||.:|:::||..|...:|
Mouse   125 ----------------------------------------QKRSRAAFSHTQVIELERKFSHQKY 149

  Fly   413 VVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKG 453
            :...||..||:||.|:|||||:||||||.|.||.|..::.|
Mouse   150 LSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSEDLG 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	30/55 (55%)
Nkx3-1	NP_035051.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..96		24/87 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	108..130		7/67 (10%)
		Homeodomain	126..182	CDD:459649	30/55 (55%)