Protein Alignment ems and Hoxa1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_034579.3
• Gene: Hoxa1 / 15394
• MGIID: 96170
• Length: 336
• Species: Mus musculus
• Alignment Length: 384
• Identity: 84/384 - (21%)
• Similarity: 117/384 - (30%)
• Gaps: 157/384 - (40%)

  Fly   103 LQAPHPHPHLSPAQQHVLHQHLLMQQQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPE 167
            :.:||.|.|         |.|                        ||:...|
Mouse    61 ISSPHHHHH---------HHH------------------------HHHPQTA------------- 79

  Fly   168 TEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPHTP---PKSVSPQSSQPSSSPTLLISSPHAT 229
            |.|....:.:....|...|:.     .||....|:.|   .:........|..:|. :.|...:|
Mouse    80 TYQTSGNLGISYSHSSCGPSY-----GAQNFSAPYGPYGLNQEADVSGGYPPCAPA-VYSGNLST 138

  Fly   230 PPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPM------PQGQPGLPD 288
            |..|....           |.|.||                  |..|.|.      .|.|..|
Mouse   139 PMVQHHHH-----------HQGYAG------------------GTVGSPQYIHHSYGQEQQTL-- 172

  Fly   289 IKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGM 353
              ||..|.|:   |.|.|..|       |.|....|.....||
Mouse   173 --ALATYNNS---LSPLHASH-------QEACRSPASETSSPA---------------------- 203

  Fly   354 ARDSYQLYPWLLSRH-----GRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYV 413
                 |.:.|:..:.     |::..:.:.|        :|..:||.|:..||.:||..|..|:|:
Mouse   204 -----QTFDWMKVKRNPPKTGKVGEYGYVG--------QPNAVRTNFTTKQLTELEKEFHFNKYL 255

  Fly   414 VGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQE-------------DEKGGEGGSQ 459
            ..|.|..:|.:|.|:|||||:||||||.|.|:.::|             |||..|...:
Mouse   256 TRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGSDEKTEESSEK 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
Hoxa1	NP_034579.3	COG5576	177..>287	CDD:227863	43/154 (28%)
		Homeodomain	234..287	CDD:459649	27/52 (52%)