Protein Alignment ems and Gsx2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_573555.1
• Gene: Gsx2 / 14843
• MGIID: 95843
• Length: 305
• Species: Mus musculus
• Alignment Length: 332
• Identity: 102/332 - (30%)
• Similarity: 129/332 - (38%)
• Gaps: 103/332 - (31%)

  Fly   220 TLLISSPHATPPQQQQQQPPPNY------PKPAMMHPGGAG-PMMMPG----------------M 261
            :|:|.......|...:..|.|::      |.|.:|...|.| |....|                .
Mouse     9 SLIIKDSSRPAPSLPESHPGPDFFIPLGMPSPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSR 73

  Fly   262 PPAGLVRPFPMGPG----------GPPMPQGQPGLPDIKALPPYINAPPEL-------------- 302
            ||||      .|.|          |..:..|...||.:|:  .:..||.:.
Mouse    74 PPAG------AGGGATGTAGAAVAGGGVAGGTGALPLLKS--QFSPAPGDAQFCPRVSHAHHHHH 130

  Fly   303 PPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSR 367
            ||||:.|.....|...|||  |......|||||||.|.|.|.|     |..|..:|.:..
Mouse   131 PPQHHHHHHQPQQPGSAAA--AAAAAAAAAAAAAALGHPQHHA-----PVCAATTYNMSD----- 183

  Fly   368 HGRIFPHRF-------PGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNL 425
                 |.||       ..:..||   ..||:||||:.:|||:||..|.||.|:....|..:|..|
Mouse   184 -----PRRFHCLSMGGSDTSQVP---NGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYL 240

  Fly   426 NLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNG----------SGDEDDDELIDMEMD 480
            ||||.|||:||||||.|||       |.|:|.| ||.|..          :..||:|.|.....:
Mouse   241 NLSEKQVKIWFQNRRVKHK-------KEGKGAS-RNNHTSCKCVGSQAHYARSEDEDSLSPASAN 297

  Fly   481 ECPSDEE 487
            |   |:|
Mouse   298 E---DKE 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	33/55 (60%)
Gsx2	NP_573555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	115..151		9/37 (24%)
		Homeodomain	204..260	CDD:459649	34/62 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..305		15/54 (28%)