Protein Alignment CG9297 and Srl

DIOPT Version :10

• Sequence 1: NP_788674.1
• Gene: CG9297 / 41688
• FlyBaseID: FBgn0038181
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_780556.2
• Gene: Srl / 106393
• MGIID: 2146620
• Length: 910
• Species: Mus musculus
• Alignment Length: 952
• Identity: 304/952 - (31%)
• Similarity: 454/952 - (47%)
• Gaps: 172/952 - (18%)

  Fly    54 GSGELQSDQPRGDDD-----DDDDDGGHSAVDEK--------------------DTIEIETVE-- 91
            |..|||.....|.:|     ::....|.::::||                    |..|.|::|
Mouse    18 GQAELQVSASGGTEDVGNLLENHFSAGDASLEEKERALYADAAPGDKNLLLHYPDGREAESLEQT 82

  Fly    92 ------------------LDSTEDAKSANDLDGDGIPDDEDD-----------DIDGDGIPNEKD 127
                              |.:|..|:||...|.:| |.:|::           .|:|   |.|:.
Mouse    83 PAGAPSTANGQGSETEASLSNTSAAESAPPGDVEG-PGEEEEGPHAAGTLPPGGIEG---PEEER 143

  Fly   128 DDIDGDGIPNDEDDDIDGDGIPNEDDDDIDGDGVPNSKDEDIDG-DGVPNSKDEDIDGDGKANHE 191
            ........|..|:   .|.|:|.|        |..:.:.|..:| .|||    |::.|
Mouse   144 PQFSSGKEPGQEE---AGVGVPTE--------GAASMEAEVQEGSSGVP----EELQG------- 186

  Fly   192 DDDLDGDGTPNH---EDEDLDGDGVPNEEDDDLDGDGKI--NHEDEDLDG--DGV-KNDEDEDLD 248
               |.|||..|.   ..|.:.....|..|..:.:|:|..  :|:..:|||  |.: ..||.|..:
Mouse   187 ---LLGDGPMNEAAGTAESVVTQSSPPIEGKEAEGEGNTGSDHQSTELDGTQDAIPAGDESEARE 248

  Fly   249 GDGKVNHEDEDLDGDGVKNEKDDDLDGDGTNNSQDEDLDGDGVPNEKDDDLDGDGILNEHDGDVD 313
            |     .||:..|                 .:.|.||....| |:.:..||..       ..|..
Mouse   249 G-----AEDKPQD-----------------YSLQSEDTATPG-PDHQPTDLHA-------ASDTA 283

  Fly   314 GDGVPNEHDHKDSGENADDDDDDDDEDDKE---------AVKKRSKREVDAAPVLDIEAPPSPAE 369
            ..||..|...::|....|.:..:..||..|         |::...:.|...|...:.::|
Mouse   284 SSGVEAEEGAEESKAEVDTESGEKVEDQGEPRPSLDAGSAIEANKQSEYTQARETENDSP----- 343

  Fly   370 EFPVEEEIVKEASAEEEAEVEAVKEEEPEQEAVQEPEPEPVVEPEAEVQPEPVQQEEEKAESAEA 434
                |.::   :...||...||..|||..:|...|....|..|...|...:....|||.:...||
Mouse   344 ----EGQV---SGMSEEGLAEASSEEEGGEEDGSENGEVPFKEESGEDSGDGASSEEEGSTPGEA 401

  Fly   435 KEEEKPAPVEEAEAEE------ESVQPEAAPKEPEAVQEEAQEDEPQTDGAQDAA--DDDDDTKP 491
            .|.:| .|......||      |.:.......:.:.::.||.|:..|..|....|  ::.:|...
Mouse   402 GEPQK-TPGATGHEEEGPQLDVEDLNTGFEGSKTQDIEAEASEERQQERGNPVIAQWEEVEDASE 465

  Fly   492 EDELLWEGHIPENRRSRQHITELLQLDEEFNAREKATDNVAEIILRDIKRIYENAVKPLETLYKY 556
            |..|          |.|.||.:.|.|:|     :|..|:.:.::.| :::||..::||||..|||
Mouse   466 EAPL----------RDRSHIDKTLMLNE-----DKPADDYSAVLQR-LRKIYHTSIKPLEQSYKY 514

  Fly   557 RDLSNRHFSDPEIFSKPLILFMGPWSGGKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNE 621
            .:|.....:|.||.|||::||:||||.|||:::|||...|.|...|.|||||:.:.|.:||.|.:
Mouse   515 NELRQHEITDGEITSKPMVLFLGPWSVGKSTMINYLLGLEDTRYQLYTGAEPTTSEFTVLMHGPK 579

  Fly   622 TEVLDGTQLAAD--YTFAGLQKFGQGLEERLRGLKMKSKILEKVNIVEIPGILEVRKQVSRVFPF 684
            .:.::|..:|||  .:|:.|:||||...|:|.|:::..|:||:|..|:.|||:|.|||..|.:||
Mouse   580 LKTIEGIVMAADSARSFSPLEKFGQNFLEKLIGIEVPHKLLERVTFVDTPGIIENRKQQERGYPF 644

  Fly   685 NDACQWFIDRADIIFLVYDPAKLDVGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGAL 749
            ||.|||||||||:||:|:||.|||||.|.|.:..||||||.|.||||||||.:..:.|:||.|||
Mouse   645 NDVCQWFIDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGAL 709

  Fly   750 IWNISPLMSSAQPPLMYTTSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKRIEHKIASARRFA 814
            .|:::||::..:||.:|.:|.|...|:......|.|.:|.:.|.||...|:.|:|:|||..|:.|
Mouse   710 FWSLAPLINVTEPPRVYVSSFWPQDYKPDTHRELFLKEEISLLEDLNQVIENRLENKIAFIRQHA 774

  Fly   815 VRVRNHAKMVDCYLNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYR 879
            :|||.||.:||.||.|:.:..|.|.:.:.:..||::.|..::|::.:...||:|::|||:.|.|:
Mouse   775 IRVRIHALLVDRYLQTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYK 839

  Fly   880 DFFRLNPLYEFKKLRDTCTYFRGCPITKLDLAIAYELPELAG 921
            |||.:||:..||.|...|:|..||.:.|::.||..|||.|.|
Mouse   840 DFFGINPISNFKLLSQQCSYMGGCFLEKIERAITQELPSLLG 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_788674.1	MSCRAMM_ClfA	<93..367	CDD:468110	68/302 (23%)
		TSP3 repeat_long	167..205	CDD:275366	12/41 (29%)
		EHD_N	539..570	CDD:465295	12/30 (40%)
		EHD	574..813	CDD:206740	118/240 (49%)
Srl	NP_780556.2	2A1904	<42..319	CDD:273344	72/335 (21%)
		2A1904	<186..469	CDD:273344	75/335 (22%)
		EHD_N	496..528	CDD:465295	13/32 (41%)
		EHD	532..773	CDD:206740	118/240 (49%)