Protein Alignment Adgf-C and ada2a

DIOPT Version :10

• Sequence 1: NP_650308.3
• Gene: Adgf-C / 41680
• FlyBaseID: FBgn0038173
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001028889.2
• Gene: ada2a / 373884
• ZFINID: ZDB-GENE-030902-4
• Length: 503
• Species: Danio rerio
• Alignment Length: 478
• Identity: 182/478 - (38%)
• Similarity: 253/478 - (52%)
• Gaps: 19/478 - (3%)

  Fly    29 RQAVLTAEEELMTGGHTHLNTEEEKVDDIFMEYKLGELAQGFRNAEQNAAALHFFKAKPLIDRSA 93
            |.|::..|....|||...||..|:.:|.     ||.:|.|....|.|...::||||||.|||:|.
Zfish    31 RDALIGLEASRRTGGDITLNEREKLLDG-----KLQKLKQHDMEAGQFPPSMHFFKAKRLIDQSP 90

  Fly    94 IFRFLQKMPKGSVLHVHNTASVSSKWVVDDLSYMPGLLRCTT--ATGQSILSFRRTPKEHKCQSQ 156
            :|..:||||||:.||||:.|.||..|:|.:::|......|.|  .|.|.|.|.........| |.
Zfish    91 VFNLIQKMPKGAALHVHDFAMVSVDWLVKNVTYRENCYVCFTDKQTVQFIFSSGPPASSSHC-SS 154

  Fly   157 YVLVSDERRNSLDRQVYDRNFERLINLYTPVPELEYPTITRVWDRFQGMFDGLSDALIYLPAFRA 221
            :.|:...|....:....|.:|.|.:.|:|..|:..||....||:||:.:|......:.|.|.|:.
Zfish   155 WTLLRSLREKIKNTTELDNSFIRNLTLFTEDPDRAYPNQDTVWERFEQVFLVAYGLVTYAPVFKD 219

  Fly   222 YHWQMLEELYNDNVMYTEIRTSFKTLYDASGRTFPRERTIHELYALNQKFMKLHPDFLGFKVIMA 286
            |.::.|.:.|.||:||.|||......|:..||...::.::.....:..:|.|.||||:|.:||..
Zfish   220 YLYEGLRQFYEDNIMYVEIRALLPQTYELDGRLNDKDWSMAACQEVVNQFKKHHPDFIGARVIFT 284

  Fly   287 VYRGYELDHLKDIVEVFKKLHQALPHFLVGFDLVGQEDKGKPLYSLLPVLR-------DLPPTAR 344
            |:|..........||....|.:..|..:.|||.|||||.|:||:.....|.       :||
Zfish   285 VHRKINATEAVKTVEEAMILRRNFPDVMAGFDFVGQEDLGRPLWYFKDALSLPEDKGFNLP---- 345

  Fly   345 LFLHGGETNWFGASTDINLLDALLMNTTRIGHGYALAKHPILLNAVKSRRIAVELSPISNQVLHL 409
            .|.|.|||:..|...|.||:||||.||||||||:|||:||::....:...:.:|:.|||||||.|
Zfish   346 YFFHAGETDSQGTDVDQNLMDALLFNTTRIGHGFALARHPVVKEMARKMYVPIEVCPISNQVLKL 410

  Fly   410 VWDLRNHPGSQFFALDVPVVICNDDPGFWNAKGLSYDFYYAIMSLAPNNAGLRLLKTLVWNSVRY 474
            |.|||:||.:...|...|:||.:|||..:.|..||:|||.|.|.....:..|..||.|..||:||
Zfish   411 VSDLRDHPAAVLMAEGHPLVISSDDPAVFGATALSHDFYEAFMGFGGMSFNLGTLKELALNSLRY 475

  Fly   475 STLTEEEQTRAFKILELSWSRFI 497
            |||:.:.:..|...|.:.|.:|:
Zfish   476 STLSSQRKEEAIDALLVKWDKFV 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-C	NP_650308.3	A_deaminase_N	4..98	CDD:462481	27/68 (40%)
		ADGF	78..493	CDD:238646	164/423 (39%)
ada2a	NP_001028889.2	adm_rel	30..502	CDD:273620	182/478 (38%)