Protein Alignment omd and Ints5

DIOPT Version :10

• Sequence 1: NP_650303.1
• Gene: omd / 41674
• FlyBaseID: FBgn0038168
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_001101046.1
• Gene: Ints5 / 309200
• RGDID: 1309370
• Length: 1019
• Species: Rattus norvegicus
• Alignment Length: 1125
• Identity: 262/1125 - (23%)
• Similarity: 410/1125 - (36%)
• Gaps: 279/1125 - (24%)

  Fly     4 QNLLDQLKHFIETVSN--GHSCPQLLTSPNLIKLALGFLEELPATRDIVFEYFALLAEISVQLYV 66
            |.|..::|.|:.....  ||.    |::....:.:|..|..||..|..|.::...:.:.||:.::
  Rat    29 QELSQEIKAFLTGADPILGHQ----LSAREHARCSLLLLRSLPPARAAVLDHLRGVFDESVRAHL 89

  Fly    67 -----SPEMADPKTGMPVSQVKLAGNRQQQQRAPEYEAFNLVKTALQSLVWKGPPAWSPLIANWS 126
                 ||....|....|.|....||....:....|      |:..|...:...|.||:|:|:.||
  Rat    90 AALEESPVAGPPHLRPPPSSHVPAGGPGLEDVVHE------VQQVLCEFIRANPKAWAPVISAWS 148

  Fly   127 LELVAKLSDKYT---QRRMTITASCN----YWLECSAMHGLMTLINSCFRKLTQPEEEACVEIML 184
            ::|:.:||..|:   ||....|.|.|    .|:.|.|...||.:...|...|.....:|||:.:|
  Rat   149 IDLMGQLSSTYSGQHQRVPHATGSLNELLQLWMGCRATRTLMDIYVQCLSALIGSCPDACVDALL 213

  Fly   185 NAFHRFPMTFDWIVARLGGCFPYKIIMQILQCGIKRFVDDYRCH--------------------- 228
            :...:....|||:||.:|..||..||.::|.||:|    |:..|
  Rat   214 DTSVQHSPHFDWVVAHIGSSFPGTIISRVLSCGLK----DFCVHSGAGGGASACGGSSSQTPSSD 274

  Fly   229 ----------------LDSEAGILDYMTSCHEQHLRAAFREMLR---------EGFAPKKPLDVA 268
                            :.|..|||.::.|.|...:|   ||:||         .|....:|...|
  Rat   275 PFPGSPAIPGEKRVPKIASVVGILGHLASRHGDSIR---RELLRMFHDSLSGGTGGRNGEPSLQA 336

  Fly   269 VVPFLLITTNYSDTILQSLVNVLVEIYTEDMCEVIVQKAPLWLS--NKMFAG-----MQPTLNNA 326
            .|||||.....|..:|.::...||:..          |.|..||  .:...|     :...||.|
  Rat   337 TVPFLLQLAVMSPALLGTVSGELVDCL----------KPPAVLSQLQQHLQGFPREELDNMLNLA 391

  Fly   327 VLRLNERGAT-------LLLTAAKMAEKYVW------------CQDFLDNSMQELEQWVLNQ--- 369
            |..:::...|       .|:..|..|.....            |...:...:..|::.|.::
  Rat   392 VHLVSQASGTGAYRLLQFLVDTAMPASVITTQGLAVPDTVREACDRLIQLLLLHLQKLVHHRGGS 456

  Fly   370 ------------RNFPLL-------ADLAYE----ETKYMLWKSCLSTNLFEQQTAVRLLLVVSS 411
                        |..|.|       .:|..|    |.|..||          |...:.||.|.:
  Rat   457 PGEGVLGPPPPPRPVPFLDALRNHVGELCGETLRLERKRFLW----------QHQLLGLLSVYT- 510

  Fly   412 QHPNIYYQTISQLLKKSYAQNPNGIGALIRLLGGQSGMVNFPGFTPGFKMVLEDITLDVQVNNRL 476
             .|:...:.:..||  |.|::|..:....:|..|                      |.|.::..|
  Rat   511 -RPSCGPEALGHLL--SRARSPEELSLATQLYAG----------------------LVVSLSGLL 550

  Fly   477 PVPPGTPTEAFNTFSNLNILARMHKSKNVAPYIKAQHLNQALNECLPKILQIFDCTVNKLVLRID 541
            |:       ||.     :.|||:|......|:......|.|                  |::..:
  Rat   551 PL-------AFR-----SCLARVHAGTLQPPFTARLLRNLA------------------LLVGWE 585

  Fly   542 RDAAE---RIADKFRAQQSKNSNNNNELCNGKDYGKRTKLEPGEDKVDDEDATRMRLAHLIVDLL 603
            :...|   .:..:|....|.:.::...|.          |.| |::|.:..|:.:.:.....:.|
  Rat   586 QQGGEGPSTLGARFGESASAHLSDLAPLL----------LHP-EEEVAEAAASLLAICPFPSEAL 639

  Fly   604 NNIEAGSRTTVLRTPLVLKLATLSVKYFFVGLTEKTVIRRAAASHRSYTLLQRQCSARKIARTVC 668
            :..:            :|.|....|..||..|........|:||.    ||.|............
  Rat   640 SPSQ------------LLGLVRAGVHRFFASLRLHGPPGVASASQ----LLTRLSQTSPAGLKAV 688

  Fly   669 LRELVERAL------FYHGHLLGQLEVYQLDELEIPEHEHLILQNLHTSS--GANSNRSVLHSGI 725
            |:.|||.||      .:.|.:.|..|...:....:.....|.:...||::  |.....||.|:|:
  Rat   689 LQLLVEGALHRGNTELFGGEMDGDNETLSIVSTPLASASLLDINRRHTAAVPGPGGIWSVFHAGV 753

  Fly   726 IGRGLRPVLPPSERNCDAEKQALY-----LKALNACCADLEKPNNVEG-----------YSLVSL 774
            |||||:|......||   .::.:|     :..|..||: ....|..||           ...|::
  Rat   754 IGRGLKPPKIVQSRN---HQEVIYNTQSLVNLLVHCCS-ASGSNEREGCWGAPTLSPEAAKAVAV 814

  Fly   775 LLVELVSTDVMYNGLPFPDEEFTRVTMERDMLIRRAFINSPVLWAVLGLIAGHRPALCYSSVLLR 839
            .|||.|..|.....|.:|.|:..|.|:|||:.|.|.|...|:|:.:|.|:|...|||||.|||||
  Rat   815 TLVESVCPDAAGAELAWPPEDHARATVERDLRIGRRFREQPLLFELLKLVAAAPPALCYCSVLLR 879

  Fly   840 ALCATCLHHWRGKNVNRFQPTAANDELMLCTKKMLQLLAMSQLIPPPLTNLHLIIEHFESAEIAL 904
            .|.|..|.||   ..:|...|..:...:..:..::.::|...|:||.|.|:|.:.......|:.|
  Rat   880 GLLAALLSHW---EASRHPDTTHSPWHLEASCILVAVMAEGSLLPPALGNMHEVFSQLAPFEVRL 941

  Fly   905 LLRECIWNYLKDHVPSPALF-HVDNNGLHWRNTNTQLAKVPPQYVDPLRHLMQRKLSTLGPHYHQ 968
            ||.. :|.:|::|.|.|..| .....|...|:.:.:.......::..|..::.|.:..||
  Rat   942 LLLS-VWGFLREHGPLPQKFIFQSERGRFIRDFSREGGGEGGPHLSVLHSVLHRNIDRLG----- 1000

  Fly   969 MFIMGELMEGDSEPDPTARL 988
                  |..|..:..|.:.|
  Rat  1001 ------LFSGRFQAPPPSTL 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
omd	NP_650303.1	INTS5_N	4..221	CDD:464341	66/230 (29%)
		INTS5_C	229..962	CDD:464342	188/821 (23%)
Ints5	NP_001101046.1	INTS5_N	29..251	CDD:464341	67/235 (29%)
		INTS5_C	290..999	CDD:464342	188/822 (23%)