DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9588 and NAS2

DIOPT Version :9

Sequence 1:	NP_650301.1	Gene:	CG9588 / 41672	FlyBaseID:	FBgn0038166	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_012259.3	Gene:	NAS2 / 854810	SGDID:	S000001269	Length:	220	Species:	Saccharomyces cerevisiae

Alignment Length:	215	Identity:	57/215 - (26%)
Similarity:	97/215 - (45%)	Gaps:	40/215 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RLERLINAKKQLEAQINRNGQILAANDNVGMSGPLVDAEGFPRNDIDVYQVRLARQTIICLQNDH 74
            :|..|:..|..:|.|:.....:| ....:||...||..:|:||:|:||.||.:.|:.:..|:||.
Yeast    30 KLSELMVLKTDIETQLEAYFSVL-EQQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDL 93

  Fly    75 KELMNQIQTLLNQYHSEIATTDPELVNRASALDLDSDRSPGGANITDLAPARAIVVVNLVSPDSP 139
            ..|:.:...||||:...:.....:          |:.|:.....|....|   ...::.|.|.||
Yeast    94 NHLLQRSHVLLNQHFDNMNVKSNQ----------DARRNNDDQAIQYTIP---FAFISEVVPGSP 145

  Fly   140 AERAGLCAGDAILRFGSINSGNFKGDLAQIGELVRNMQSQNVQLKVKRGE------------QQL 192
            :::|.:...|.::..|::::.|             :.:.||:|:.|.:.|            |.|
Yeast   146 SDKADIKVDDKLISIGNVHAAN-------------HSKLQNIQMVVMKNEDRPLPVLLLREGQIL 197

  Fly   193 DLILVP-KTWSGRGLLGCNI 211
            ...|.| :.|:|||||||.|
Yeast   198 KTSLTPSRNWNGRGLLGCRI 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9588	NP_650301.1	PDZ	116..186	CDD:238080	13/69 (19%)
NAS2	NP_012259.3	Nas2_N	31..109	CDD:408080	27/78 (35%)
NAS2	NP_012259.3	PDZ	106..182	CDD:395476	17/101 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344316
Domainoid	1	1.000	52	1.000	Domainoid score	I2825
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2106
Inparanoid	1	1.050	81	1.000	Inparanoid score	I1611
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54093
OrthoFinder	1	1.000	-	-		FOG0004887
OrthoInspector	1	1.000	-	-		oto99269
orthoMCL	1	0.900	-	-		OOG6_102356
Panther	1	1.100	-	-	LDO	PTHR12651
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1021
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790